Engineering Biosystems With Emergent Collective Features

2-Ketoglutarate-Generated In Vitro Enzymatic Biosystem Facilitates Fe(II)/2-Ketoglutarate-Dependent Dioxygenase-Mediated C-H Bond Oxidation for (2 s,3 r,4 s)-4-Hydroxyisoleucine Synthesis

Fe(II)/2-ketoglutarate-dependent dioxygenase (Fe(II)/2-KG DO)-mediated hydroxylation is a important kind of C-H bond functionalization for synthesizing hydroxy amino acids used as pharmaceutical uncooked supplies and precursors. Nevertheless, DO exercise requires 2-ketoglutarate (2-KG), lack of which reduces the effectivity of Fe(II)/2-KG DO-mediated hydroxylation.

Right here, we performed multi-enzymatic syntheses of hydroxy amino acids. Utilizing (2s,3r,4s)-4-hydroxyisoleucine (4-HIL) as a mannequin product, we coupled regio- and stereo-selective hydroxylation of l-Ile by the dioxygenase IDO with 2-KG technology from available l-Glu by l-glutamate oxidase (LGOX) and catalase (CAT).

Within the one-pot system, H2O2 considerably inhibited IDO exercise and elevated Fe2+ concentrations of severely repressed LGOX. A sequential cascade response was preferable to a single-step course of as CAT within the former system hydrolyzed H2O2. We obtained 465 mM 4-HIL at 93% yield within the two-step system.

Furthermore, this course of facilitated C-H hydroxylation of a number of hydrophobic aliphatic amino acids to supply hydroxy amino acids, and C-H sulfoxidation of sulfur-containing l-amino acids to yield l-amino acid sulfoxides. Thus, we constructed an environment friendly cascade response to supply 4-HIL by offering prerequisite 2-KG from low-cost and plentiful l-Glu and developed a method for creating enzymatic programs catalyzing 2-KG-dependent reactions in sustainable bioprocesses that synthesize different purposeful compounds.

Towards Engineering Biosystems With Emergent Collective Features

Many advanced behaviors in organic programs emerge from massive populations of interacting molecules or cells, producing capabilities that transcend the capabilities of the person elements. Such collective phenomena are of nice curiosity to bioengineers because of their robustness and scalability.

Nevertheless, engineering emergent collective capabilities is troublesome as a result of they come up as a consequence of advanced multi-level suggestions, which regularly spans many length-scales. Right here, we current a perspective on how a few of these challenges could possibly be overcome through the use of multi-agent modeling as a design framework inside artificial biology.

Utilizing case research protecting the development of artificial ecologies to organic computation and artificial cellularity, we present how multi-agent modeling can seize the core options of advanced multi-scale programs and supply novel insights into the underlying mechanisms which information emergent functionalities throughout scales. The flexibility to unravel design guidelines underpinning these behaviors gives a method to take artificial biology past single molecules or cells and towards the creation of programs with capabilities that may solely emerge from collectives at a number of scales.

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uwmembraneprotein

human CD163 antigen,CD163 LISA kit

201-12-0247 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

human CD163 antigen,CD163 ELISA kit

YLA0098HU-48T 48T Ask for price

human CD163 antigen,CD163 ELISA kit

YLA0098HU-96T 96T Ask for price

Human CD163 Antigen, CD163 GENLISA ELISA

KBH0246 1 x 96 wells
EUR 286

Mouse Anti Human Cd163 Monoclonal Antibody

CABT-47162MH 25 µg
EUR 446.4

Mouse Anti Human Cd163 Monoclonal Antibody

CABT-47163MH 0.2 mg
EUR 1057.2

PE anti-human CD163

E16FHP163-025 25 tests
EUR 433.33
Description: Available in various conjugation types.

PE anti-human CD163

E16FHP163-100 100 tests
EUR 953.33
Description: Available in various conjugation types.

Anti-Human CD163 Antibody

101-M291 100 µg
EUR 399
Description: CD163, also known as hemoglobin scavenger receptor, is a type I transmembrane protein expressed exclusively in monocytes and macrophages. It is a scavenger receptor cysteine-rich superfamily (SRCR-SF) protein that contains nine SRCR motifs in its extracellular region. Two alternatively spliced cytoplasmic variants of human CD163 exist. A soluble form of CD163 can also be released by metalloproteinase-mediated shedding of the extracellular domain. CD163 mediates the endocytosis of haptoglobin-hemoglobin complexes.

APC anti-human CD163

E16FHA163-025 25 tests
EUR 520
Description: Available in various conjugation types.

APC anti-human CD163

E16FHA163-100 100 tests
EUR 1191.67
Description: Available in various conjugation types.

FITC anti-human CD163

E16FHF163-025 25 tests
EUR 520
Description: Available in various conjugation types.

FITC anti-human CD163

E16FHF163-100 100 tests
EUR 1191.67
Description: Available in various conjugation types.

Biotin anti-human CD163

E16FHB163-025U 25 μg
EUR 346.67
Description: Available in various conjugation types.

Biotin anti-human CD163

E16FHB163-100U 100 μg
EUR 780
Description: Available in various conjugation types.

Purified anti-human CD163

E16FHU163-100U 100 μg
EUR 433.33
Description: Available in various conjugation types.

CD163 (untagged)-Human CD163 molecule (CD163), transcript variant 1

SC117495 10 µg Ask for price

CD163 (untagged)-Human CD163 molecule (CD163), transcript variant 2

SC308167 10 µg Ask for price

CD163 (GFP-tagged) - Human CD163 molecule (CD163), transcript variant 2

RG212754 10 µg Ask for price

CD163 (GFP-tagged) - Human CD163 molecule (CD163), transcript variant 1

RG208557 10 µg Ask for price

Rabbit Anti Human CD163 Monoclonal Clone ABCC-3

IRBAHUCD163ABCC3C100UL each
EUR 496
Description: Rabbit Anti Human CD163 Monoclonal Clone ABCC-3

Recombinant Human CD163/CD163 Protein, His Tag

E40KMH346 20ug
EUR 495

PE-Cy7 anti-human CD163

E16FHN163-025 25 tests
EUR 650
Description: Available in various conjugation types.

PE-Cy7 anti-human CD163

E16FHN163-100 100 tests
EUR 1408.33
Description: Available in various conjugation types.

APC-Cy7 anti-human CD163

E16FHO163-025 25 tests
EUR 650
Description: Available in various conjugation types.

APC-Cy7 anti-human CD163

E16FHO163-100 100 tests
EUR 1408.33
Description: Available in various conjugation types.

CD163 (Myc-DDK-tagged)-Human CD163 molecule (CD163), transcript variant 1

RC208557 10 µg Ask for price

CD163 (Myc-DDK-tagged)-Human CD163 molecule (CD163), transcript variant 2

RC212754 10 µg Ask for price

PerCP-Cy5.5 anti-human CD163

E16FHS163-025 25 tests
EUR 541.67
Description: Available in various conjugation types.

PerCP-Cy5.5 anti-human CD163

E16FHS163-100 100 tests
EUR 1278.33
Description: Available in various conjugation types.

Mouse Monoclonal anti-human CD163

hAP-0161 100ug
EUR 250

Mouse Monoclonal anti-human CD163

hAP-0161A 50ug
EUR 400

Human CD163 Protein

E40KMPH6242 20ug
EUR 495

anti- CD163/M130 Antibody

FNab09771 100µg
EUR 658.5
Description: Antibody raised against CD163/M130 

Anti-Hu CD163 PE

1P-645-T025 25 tests
EUR 121

Anti-Hu CD163 PE

1P-645-T100 100 tests
EUR 242

Anti-Hu CD163 APC

1A-645-T025 25 tests
EUR 121

Anti-Hu CD163 APC

1A-645-T100 100 tests
EUR 242

Anti-Hu CD163 Purified

11-645-C025 0.025 mg
EUR 71.5

Anti-Hu CD163 Purified

11-645-C100 0.1 mg
EUR 143

Human CD163, Fc Tag

E24PHA282 50 μg
EUR 250

Human CD163, His Tag

E24PHA281 50 μg
EUR 250

Mouse Monoclonal anti-Human CD163 Antibody

xAP-0134 100ug
EUR 280

Mouse Monoclonal anti-Human CD163 Antibody

xAP-0135 100ug
EUR 280

Human CD163 ELISA Kit

EK5296 96 tests
EUR 599

Human CD163 ELISA Kit

ELA-E1726h 96 Tests
EUR 988.8

Human CD163 ELISA Kit

LF-EK50890 1×96T
EUR 777.6

Human CD163 ELISA Kit

GWB-SKR207 96 Tests Ask for price

Human CD163 shRNA Plasmid

20-abx956176
  • Ask for price
  • Ask for price
  • 150 µg
  • 300 µg

CD163 Antigen (CD163) Rabbit anti-Human Polyclonal (N-Terminus) (K20-T) Antibody

GWB-B1E200 0.05 ml Ask for price

CD163 (Human) ELISA Kit

EKA52023-5x96T 5x96T Ask for price

CD163 (Human) ELISA Kit

EKA52023-96T 96T
EUR 446.9

Recombinant Human CD163 Protein

RP02295 500μg
EUR 1625

Human CellExp? CD163, Human recombinant

9226-10 each
EUR 366

Human CellExp? CD163, Human recombinant

9226-50 each
EUR 927.6

PE Anti-human CD163 Antibody *GHI/61*

116301K0 25 tests
EUR 391
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE Anti-human CD163 Antibody *GHI/61*

116301K0-25tests 25 tests
EUR 383
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE Anti-human CD163 Antibody *GHI/61*

116301K1 100 tests
EUR 1015
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE Anti-human CD163 Antibody *GHI/61*

116301K1-100tests 100 tests
EUR 995
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE Anti-human CD163 Antibody *GHI/61*

116301K2 500 tests
EUR 3044
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE Anti-human CD163 Antibody *GHI/61*

116301K2-500tests 500 tests
EUR 2984
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B0 25 tests
EUR 391
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B0-25tests 25 tests
EUR 383
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B1 100 tests
EUR 1015
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B1-100tests 100 tests
EUR 995
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B2 500 tests
EUR 3044
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC Anti-human CD163 Antibody *GHI/61*

116301B2-500tests 500 tests
EUR 2984
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Alexa Fluor® 647 anti-human CD163

E16FHK163-025 25 tests
EUR 433.33
Description: Available in various conjugation types.

Alexa Fluor® 647 anti-human CD163

E16FHK163-100 100 tests
EUR 975
Description: Available in various conjugation types.

FITC Anti-human CD163 Antibody *GHI/61*

116301G0 100 tests
EUR 558
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

FITC Anti-human CD163 Antibody *GHI/61*

116301G0-100tests 100 tests
EUR 547
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

FITC Anti-human CD163 Antibody *GHI/61*

116301G1 500 tests
EUR 2093
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

FITC Anti-human CD163 Antibody *GHI/61*

116301G1-500tests 500 tests
EUR 2051
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

TRITC Anti-human CD163 Antibody *GHI/61*

116301H0 100 tests
EUR 558
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

TRITC Anti-human CD163 Antibody *GHI/61*

116301H0-100tests 100 tests
EUR 547
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

TRITC Anti-human CD163 Antibody *GHI/61*

116301H1 500 tests
EUR 2093
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

TRITC Anti-human CD163 Antibody *GHI/61*

116301H1-500tests 500 tests
EUR 2051
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S0 25 tests
EUR 391
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S0-25tests 25 tests
EUR 383
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S1 100 tests
EUR 1015
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S1-100tests 100 tests
EUR 995
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S2 500 tests
EUR 3044
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP Anti-human CD163 Antibody *GHI/61*

116301S2-500tests 500 tests
EUR 2984
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I0 100 tests
EUR 558
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I0-100tests 100 tests
EUR 547
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I1 500 tests
EUR 2093
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacBlue Anti-human CD163 Antibody *GHI/61*

116301I1-500tests 500 tests
EUR 2051
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Purified Anti-human CD163 Antibody *GHI/61*

11630000 100 ug
EUR 373
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Purified Anti-human CD163 Antibody *GHI/61*

11630000-100ug 100 ug
EUR 365
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J0 100 tests
EUR 558
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J0-100tests 100 tests
EUR 547
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J1 500 tests
EUR 2093
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PacOrange Anti-human CD163 Antibody *GHI/61*

116301J1-500tests 500 tests
EUR 2051
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Mouse Anti-Human CD163 Purified (100 ug)

TA320238 100 µg Ask for price

Human CD163 Protein, His Tag

CD3-H52E8 1mg
EUR 374.5
Description: Human CD163, His Tag (CD3-H52E8) is expressed from human 293 cells (HEK293). It contains AA Ser 42 - Ser 1045 (Accession # Q86VB7).

Human CD163 PicoKine ELISA Kit

EK0715 96 wells
EUR 510
Description: For quantitative detection of human CD163 in cell culture supernates, serum and plasma(heparin).

Human CD163 knockout cell line

ABC-KH2671 1 vial Ask for price
Description: Human CD163 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human CD163 knockdown cell line

ABC-KD2671 1 vial Ask for price
Description: Human CD163 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human CD163 Protein Lysate 20ug

IHUCD163PLLY20UG each
EUR 213
Description: Human CD163 Protein Lysate 20ug

Mouse Recombinant anti-Human CD163 Recombinant Antibody

xAP-0136 100ug
EUR 280

CD163 ORF Vector (Human) (pORF)

ORF017045 1.0 ug DNA
EUR 486

Canine CD163 antigen(CD163 LISA kit

GA-E0062CN-48T 48T
EUR 482.4

Canine CD163 antigen(CD163 LISA kit

GA-E0062CN-96T 96T
EUR 820.8

Porcine CD163 antigen,CD163 LISA kit

GA-E0045PC-48T 48T
EUR 436.8

Porcine CD163 antigen,CD163 LISA kit

GA-E0045PC-96T 96T
EUR 708

Porcine CD163 antigen, CD163 LISA kit

KLP0040 1 x 96 wells
EUR 341

Porcine CD163 antigen,CD163 LISA kit

YLA0139PO-48T 48T Ask for price

Porcine CD163 antigen,CD163 LISA kit

YLA0139PO-96T 96T Ask for price

Rat CD163 antigen, CD163 GENLISA ELISA

KLR2081 1 x 96 wells
EUR 341

Cd163 (untagged) - Mouse CD163 antigen (Cd163), transcript variant 2, (10ug)

MC223654 10 µg Ask for price

Cd163 (untagged) - Mouse CD163 antigen (Cd163), transcript variant 1, (10ug)

MC223773 10 µg Ask for price

CD163 ELISA Kit (Human) (OKCD07621)

OKCD07621 96 Wells
EUR 1123.2
Description: Description of target: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: < 0.273ng/mL

CD163 ELISA Kit (Human) (OKAN04666)

OKAN04666 96 Wells
EUR 950.4
Description: Description of target: The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich ELISA;Sensitivity: 0.273 ng/mL

CD163 ELISA Kit (Human) (OKBB00786)

OKBB00786 96 Wells
EUR 606
Description: Description of target: CD163(Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. It has also been shown to mark cells of monocyte/macrophage lineage. CD163, a member of the scavenger receptor cysteine-rich(SRCR) superfamily, is exclusively expressed by monocytes and macrophages. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, CD163 gene was mapped the to chromosome 12p13.3. CD163 is upregulated in a large range of diseases inflammatory diseases including type 2 diabetes, macrophage activation sickness, Tangier's disease, reumatoid arthritis etc.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <150pg/ml

CD163 ELISA Kit (Human) (OKBB01513)

OKBB01513 96 Wells
EUR 684
Description: Description of target: CD163(Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. It has also been shown to mark cells of monocyte/macrophage lineage. CD163, a member of the scavenger receptor cysteine-rich(SRCR) superfamily, is exclusively expressed by monocytes and macrophages. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, CD163 gene was mapped the to chromosome 12p13.3. CD163 is upregulated in a large range of diseases inflammatory diseases including type 2 diabetes, macrophage activation sickness, Tangier's disease, reumatoid arthritis etc.;Species reactivity: Human;Application: ELISA;Assay info: ;Sensitivity: <150pg/ml

PE/Cy5 Anti-human CD163 Antibody *GHI/61*

116301L0 25 tests
EUR 438
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy5 Anti-human CD163 Antibody *GHI/61*

116301L0-25tests 25 tests
EUR 429
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy5 Anti-human CD163 Antibody *GHI/61*

116301L1 100 tests
EUR 1140
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy5 Anti-human CD163 Antibody *GHI/61*

116301L1-100tests 100 tests
EUR 1117
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy5 Anti-human CD163 Antibody *GHI/61*

116301L2 500 tests
EUR 3419
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy5 Anti-human CD163 Antibody *GHI/61*

116301L2-500tests 500 tests
EUR 3351
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy7 Anti-human CD163 Antibody *GHI/61*

116301M0 25 tests
EUR 438
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy7 Anti-human CD163 Antibody *GHI/61*

116301M0-25tests 25 tests
EUR 429
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy7 Anti-human CD163 Antibody *GHI/61*

116301M1 100 tests
EUR 1140
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy7 Anti-human CD163 Antibody *GHI/61*

116301M1-100tests 100 tests
EUR 1117
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy7 Anti-human CD163 Antibody *GHI/61*

116301M2 500 tests
EUR 3419
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PE/Cy7 Anti-human CD163 Antibody *GHI/61*

116301M2-500tests 500 tests
EUR 3351
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

QuickDetect? CD163 (Human) ELISA Kit

K4422-100 each
EUR 966

APC/Cy7 Anti-human CD163 Antibody *GHI/61*

116301C0 25 tests
EUR 438
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC/Cy7 Anti-human CD163 Antibody *GHI/61*

116301C0-25tests 25 tests
EUR 429
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC/Cy7 Anti-human CD163 Antibody *GHI/61*

116301C1 100 tests
EUR 1140
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC/Cy7 Anti-human CD163 Antibody *GHI/61*

116301C1-100tests 100 tests
EUR 1117
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC/Cy7 Anti-human CD163 Antibody *GHI/61*

116301C2 500 tests
EUR 3419
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

APC/Cy7 Anti-human CD163 Antibody *GHI/61*

116301C2-500tests 500 tests
EUR 3351
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Lenti ORF particles, CD163 (mGFP-tagged) - Human CD163 molecule (CD163), transcript variant 1, 200ul, >10^7 TU/mL

RC208557L2V 200 µl Ask for price

Lenti ORF particles, CD163 (mGFP-tagged) - Human CD163 molecule (CD163), transcript variant 1, 200ul, >10^7 TU/mL

RC208557L4V 200 µl Ask for price

PerCP/Cy5.5 Anti-human CD163 Antibody *GHI/61*

116301T0 25 tests
EUR 438
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP/Cy5.5 Anti-human CD163 Antibody *GHI/61*

116301T0-25tests 25 tests
EUR 429
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP/Cy5.5 Anti-human CD163 Antibody *GHI/61*

116301T1 100 tests
EUR 1140
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP/Cy5.5 Anti-human CD163 Antibody *GHI/61*

116301T1-100tests 100 tests
EUR 1117
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP/Cy5.5 Anti-human CD163 Antibody *GHI/61*

116301T2 500 tests
EUR 3419
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

PerCP/Cy5.5 Anti-human CD163 Antibody *GHI/61*

116301T2-500tests 500 tests
EUR 3351
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Anti-Hu CD163 PE-Cy™7

T7-645-T025 25 tests
EUR 137.5

Anti-Hu CD163 PE-Cy™7

T7-645-T100 100 tests
EUR 275

mFluorâ„¢ UV375 Anti-human CD163 Antibody *GHI/61*

116300X0 100 tests
EUR 558
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

mFluorâ„¢ UV375 Anti-human CD163 Antibody *GHI/61*

116300X1 500 tests
EUR 2093
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

mFluorâ„¢ UV460 Anti-human CD163 Antibody *GHI/61*

116300Y0 100 tests
EUR 558
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

mFluorâ„¢ UV460 Anti-human CD163 Antibody *GHI/61*

116300Y1 500 tests
EUR 2093
Description: GHI/61 is an anti-human monoclonal antibody that forms an immune complex with the CD163 antigen.

Anti-Hu CD163 PerCP-Cy™5.5

T9-645-T025 25 tests
EUR 165

Anti-Hu CD163 PerCP-Cy™5.5

T9-645-T100 100 tests
EUR 330

PerCP/Cyanine5.5 Anti-Human CD163 Antibody[GHI/61]

E-AB-F1298J-100Tests 100Tests
EUR 300
Description: FCM

PerCP/Cyanine5.5 Anti-Human CD163 Antibody[GHI/61]

E-AB-F1298J-100Tests2 100Tests×2
EUR 450
Description: FCM

PerCP/Cyanine5.5 Anti-Human CD163 Antibody[GHI/61]

E-AB-F1298J-20Tests 20Tests
EUR 120
Description: FCM

APC Anti-Mouse CD163 Antibody[S15049F]

E-AB-F1295E-100Tests 100Tests
EUR 145
Description: FCM

APC Anti-Mouse CD163 Antibody[S15049F]

E-AB-F1295E-100Tests2 100Tests×2
EUR 220
Description: FCM

APC Anti-Mouse CD163 Antibody[S15049F]

E-AB-F1295E-50Tests 50Tests
EUR 85
Description: FCM

APC Anti-Mouse CD163 Antibody[S15049F]

E-AB-F1295UE-100ug 100ug
EUR 360
Description: FCM

APC Anti-Mouse CD163 Antibody[S15049F]

E-AB-F1295UE-25ug 25ug
EUR 100
Description: FCM

APC Anti-Mouse CD163 Antibody[S15049F]

E-AB-F1295UE-each each Ask for price
Description: FCM

CD163 antibody

10R-6496 100 ug
EUR 156
Description: Mouse monoclonal CD163 antibody

CD163 antibody

10R-CD163aRT 250 ug Ask for price
Description: Mouse monoclonal CD163 antibody

Cd163 Antibody

1-CSB-PA650452LA01MO
  • Ask for price
  • Ask for price
  • 100ug
  • 50ug
Description: A polyclonal antibody against Cd163. Recognizes Cd163 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB; Recommended dilution: WB:1:500-1:2000

CD163 Antibody

1-CSB-PA969205
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:25-1:100

CD163 Antibody

E037157 100μg/100μl
EUR 255
Description: Available in various conjugation types.

CD163 Antibody

E19-8235-1 50ug/50ul
EUR 145
Description: Available in various conjugation types.

CD163 Antibody

E19-8235-2 100ug/100ul
EUR 225
Description: Available in various conjugation types.

CD163 Antibody

F50316-0.08ML 0.08 ml
EUR 140.25
Description: CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. It also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.

CD163 Antibody

F50316-0.4ML 0.4 ml
EUR 322.15
Description: CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype. It also induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization, inositol triphosphate production and secretion of IL6 and CSF1.

CD163 Antibody

DF8235 200ul
EUR 420

CD163 Antibody

DF8235-100ul 100ul
EUR 280

CD163 Antibody

DF8235-200ul 200ul
EUR 350

CD163 Antibody

E38PA9656 100ul
EUR 225
Description: Available in various conjugation types.

CD163 Antibody

E39-10799 100ug/100ul
EUR 225
Description: Available in various conjugation types.

CD163 Antibody

37157 100ul
EUR 319

CD163 Antibody

37157-100ul 100ul
EUR 302.4

CD163 Antibody

49553 100ul
EUR 499

CD163 Antibody

49553-100ul 100ul
EUR 399.6

CD163 Antibody

49553-50ul 50ul
EUR 286.8

CD163 Antibody

ABD8235 100 ug
EUR 525.6

CD163 Antibody

1-CSB-PA801238LA01HU
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against CD163. Recognizes CD163 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF; Recommended dilution: IF:1:50-1:200

CD163 Antibody

20-abx242956
  • Ask for price
  • Ask for price
  • 100 ul
  • 50 ul

CD163 Antibody

RQ4259 100 ug
EUR 356.15
Description: CD163 (Cluster of Differentiation 163) is a protein that in humans is encoded by the CD163 gene. The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

CD163 Antibody

GWB-BFAF4C 0.2 mg Ask for price

CD163 Antibody

GWB-C1B36B 0.025 mg Ask for price

CD163 Antibody

R20390-0.1ML 100ul
EUR 409

CD163 Antibody

R30973 100 ug
EUR 356.15
Description: CD163 (Cluster of Differentiation 163) is a human protein encoded by the CD163 gene. The receptor belongs to the scavenger receptor cysteine rich family type B and consists of an 1048 amino acid residues extracellular domain, a single transmembrane segment and a cytoplasmic tail with several splice variants. CD163 is a scavenger receptor for the hemoglobin-haptoglobincomplex. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, Stover et al.(2000) mapped the CD163 gene to chromosome 12p13.3. Specific CD163-mediated endocytosis of haptoglobin-hemoglobin complexes was measurable in cells transfected with CD163 cDNA and in CD163-expressing myelomonocytic lymphoma cells.CD163 expression in monocytes promoted bacteria-induced proinflammatory cytokine production that could be blocked by anti-CD163 antibodies. Cells expressing human CD163 and recombinant protein containing the extracellular domain of CD163 supported adhesion of erythroblastic cells.

CD163 Antibody

R30974 100 ug
EUR 356.15
Description: Cluster of Differentiation 163, also known as Hemoglobin scavenger receptor, is a human protein encoded by the CD163 gene. The receptor belongs to the scavenger receptor cysteine rich family type B and consists of an 1048 amino acid residues extracellular domain, a single transmembrane segment and a cytoplasmic tail with several splice variants. CD163 is a scavenger receptorfor the hemoglobin-haptoglobin complex. Using FISH, somatic cell hybrid analysis, and radiation hybrid analysis, Stover et al.(2000) mapped the gene to chromosome 12p13.3. CD163 expression in monocytes promoted bacteria-induced proinflammatory cytokine production that could be blocked by CD163 antibody. Cells expressing human CD163 and recombinant protein containing the extracellular domain of CD163 supported adhesion of erythroblastic cells.

CD163 Antibody

V8757-100UG 100 ug
EUR 349.3
Description: CD163 is a type I membrane protein, and is a member of the hemoglobin scavenger receptor cystein-rich superfamily. The protein is involved in the clearance of hemoglobin-haptoglobin complexes and is considered to have anti-inflammatory functions. CD163 expression is restricted to the monocytic/macrophage lineage. It is expressed by all circulating monocytes and by a majority of tissue macrophages, such as splenic dendrocytes, alveolar macrophages and Kupffer cells of the liver. It is not present in macrophages in the mantle zone and some of the germinal center cells in lymph follicles, nor in Langerhans cells and interdigitating reticulum cells. In tumor tissues, CD163 is found in almost all cases of acute myeloid leukemia with monocytoid differentiation and in the majority of cases of histiocytic sarcoma, littoral cell angioma, Rosai-Dorfman disease, Langerhans cell histiocytosis and typical and atypical fibrous histiocytoma. It is also expressed in some cases of dermatofibrosarcoma protuberans. CD163 can be used to detect cells of monocytic and histiocyte lineage in neoplastic and reactive lesions. It has been shown to be more sensitive than CD68 for the detection of macrophages and monocytic cells. It covers a similar, but not identical, spectrum of cells as CD68.

CD163 Antibody

V8757-20UG 20 ug
EUR 153.3
Description: CD163 is a type I membrane protein, and is a member of the hemoglobin scavenger receptor cystein-rich superfamily. The protein is involved in the clearance of hemoglobin-haptoglobin complexes and is considered to have anti-inflammatory functions. CD163 expression is restricted to the monocytic/macrophage lineage. It is expressed by all circulating monocytes and by a majority of tissue macrophages, such as splenic dendrocytes, alveolar macrophages and Kupffer cells of the liver. It is not present in macrophages in the mantle zone and some of the germinal center cells in lymph follicles, nor in Langerhans cells and interdigitating reticulum cells. In tumor tissues, CD163 is found in almost all cases of acute myeloid leukemia with monocytoid differentiation and in the majority of cases of histiocytic sarcoma, littoral cell angioma, Rosai-Dorfman disease, Langerhans cell histiocytosis and typical and atypical fibrous histiocytoma. It is also expressed in some cases of dermatofibrosarcoma protuberans. CD163 can be used to detect cells of monocytic and histiocyte lineage in neoplastic and reactive lesions. It has been shown to be more sensitive than CD68 for the detection of macrophages and monocytic cells. It covers a similar, but not identical, spectrum of cells as CD68.

CD163 Antibody

V8757SAF-100UG 100 ug
EUR 349.3
Description: CD163 is a type I membrane protein, and is a member of the hemoglobin scavenger receptor cystein-rich superfamily. The protein is involved in the clearance of hemoglobin-haptoglobin complexes and is considered to have anti-inflammatory functions. CD163 expression is restricted to the monocytic/macrophage lineage. It is expressed by all circulating monocytes and by a majority of tissue macrophages, such as splenic dendrocytes, alveolar macrophages and Kupffer cells of the liver. It is not present in macrophages in the mantle zone and some of the germinal center cells in lymph follicles, nor in Langerhans cells and interdigitating reticulum cells. In tumor tissues, CD163 is found in almost all cases of acute myeloid leukemia with monocytoid differentiation and in the majority of cases of histiocytic sarcoma, littoral cell angioma, Rosai-Dorfman disease, Langerhans cell histiocytosis and typical and atypical fibrous histiocytoma. It is also expressed in some cases of dermatofibrosarcoma protuberans. CD163 can be used to detect cells of monocytic and histiocyte lineage in neoplastic and reactive lesions. It has been shown to be more sensitive than CD68 for the detection of macrophages and monocytic cells. It covers a similar, but not identical, spectrum of cells as CD68.

CD163 Antibody

V3937-100UG 100 ug
EUR 349.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V3937-20UG 20 ug
EUR 153.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V3937SAF-100UG 100 ug
EUR 349.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V7470-100UG 100 ug
EUR 349.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V7470-20UG 20 ug
EUR 153.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V7470IHC-7ML 7 ml
EUR 424.15
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V7470SAF-100UG 100 ug
EUR 349.3
Description: This antibody recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

CD163 Antibody

V8227-100UG 100 ug
EUR 349.3
Description: This MAb recognizes a protein of 140kDa, identified as CD163. It has been identified as an acute phase-regulated transmembrane protein whose function is to mediate the endocytosis of haptoglobin-hemoglobin complexes. This receptor is expressed on the surface of monocytes with low expression and on tissue macrophages, histiocytes with high expression. Staining with anti-CD163 has been helpful to distinguish synovial macrophages from synovial intimal fibroblasts in rheumatoid arthritis, where its specificity for macrophages was found to be superior to that of anti-CD68. Increased levels of CD163 were also detected in patients with microbial infections and myelomonocytic leukemias. Anti-CD163 is of considerable value for selective identification of monocytes and macrophages at a certain stage of differentiation and is suitable for diagnosing myelomonocytic or monocytic leukaemia and neoplasms of true histiocytic origin. CD163 is positive in skin (histiocytes), gut, Kupffer cells, a few alveolar macrophages, macrophages in the placenta, and in macrophages in inflamed tissues including tumor tissue.

Understanding the interplay of polyelectrolyte architectures with proteins and biosystems

  • Polyelectrolytes reminiscent of e.g. DNA or heparin are lengthy linear or branched macromolecules onto which prices are appended. The counterions neutralizing these prices could dissociate in water and can largely decide the interplay of such polyelectrolytes with biomolecules and particularly with proteins.
  • Right here we assessment research on the interplay of proteins with polyelectrolytes and the way this data can be utilized for medical purposes.

Counterion launch was recognized as the principle driving power for the binding of proteins to polyelectrolytes: Patches of constructive cost develop into multivalent counterions of the polyelectrolyte which results in the discharge of counterions of the polyelectrolyte and a concomitant enhance of entropy.

We present this by surveying investigations completed on the interplay of proteins with pure and artificial polyelectrolytes. Particular emphasis is laid on sulfated dendritic polyglycerols (dPGS). The complete overview demonstrates that we’re shifting on to a higher understanding of charge-charge interplay in system of organic relevance. Therefore, analysis alongside these strains will support and promote the design of artificial polyelectrolytes for medical purposes.

Synthetic Biosystems by Printing Biology

The continual progress of printing applied sciences over the previous 20 years has fueled the event of a plethora of purposes in supplies sciences, versatile electronics, and biotechnologies. Extra lately, printing methodologies have began as much as discover the world of Synthetic Biology, providing new paradigms within the direct meeting of Synthetic Biosystems (small condensates, compartments, networks, tissues, and organs) by mimicking the results of the evolution of dwelling programs and likewise by redesigning pure organic programs, taking inspiration from them.

This latest progress is reported by way of a brand new discipline right here outlined as Printing Biology, ensuing from the intersection between the sector of printing and the underside up Artificial Biology. Printing Biology explores new approaches for the reconfigurable meeting of designed life-like or life-inspired buildings.

This work presents this rising discipline, highlighting its essential options, i.e., printing methodologies (from 2D to 3D), molecular ink properties, deposition mechanisms, and eventually the purposes and future problems. Printing Biology is anticipated to point out a rising affect on the event of biotechnology and life-inspired fabrication.

Anti-Human IL-8 Antibody

102-P38 100 µg
EUR 245.7
Description: Il-8 or CXCL8 was originally discovered and purified as a neutrophil chemotactic and activating factor. It was also referred to as neutrophil chemotactic factor (NCF), neutrophil activating protein (NAP), monocytederived neutrophil chemotactic factor (MDNCF), T lymphocyte chemotactic factor (TCF), granulocyte chemotactic protein (GCP) and leukocyte adhesion inhibitor (LAI). Many cell types, including monocyte/macrophages, T cells, neutrophils, fibroblasts, endothelial cells, keratinocytes, hepatocytes, chondrocytes, and various tumor cell lines, can produce CXCL8 in response to a wide variety of proinflammatory stimuli such as exposure to IL-1, TNF, LPS, and viruses. CXCL8 is a member of the alpha (CXC) subfamily of chemokines, which also includes platelet factor-4, GRO, and IP10.

Anti-Human IL-8 Antibody

GWB-817E77 1 mL Ask for price

Human Interleukin-8 (IL-8) Antibody

13102-05011 150 ug
EUR 175

Human IL-8

90258-A 5 µg
EUR 130
Description: Recombinant human Interleukin-8 is a disulfide-linked monomer protein consisting of 78 amino acid residues, migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Interleukin-8 mature chain was expressed in E. coli.

Human IL-8

90258-B 25 µg
EUR 205
Description: Recombinant human Interleukin-8 is a disulfide-linked monomer protein consisting of 78 amino acid residues, migrates as an approximately 9 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Interleukin-8 mature chain was expressed in E. coli.

human IL-8

M851530020 1 unit
EUR 804.84

Anti-CXCL8 / IL-8 Reference Antibody (Genentech anti-IL-8)

E24CHA784 100 μg
EUR 225
Description: Available in various conjugation types.

human-anti-human-IL-8-mAb(1H)

E409C16-hA100 Inflammation-Storm-Antibodies
EUR 276.5
Description: Inflammation Storm Antibodies

human-anti-human-IL-8-mAb(2H)

E409C16-hB100 Inflammation-Storm-Antibodies
EUR 276.5
Description: Inflammation Storm Antibodies

Anti-IL-8 Antibody

A00423 1 mL
EUR 1444.8
Description: Rabbit Polyclonal IL-8 Antibody. Validated in IP, WB and tested in Human.

Anti-IL-8 Antibody

A2062-100 100 µg
EUR 472.8

Anti-IL-8 Antibody

ER1706-67 100ul
EUR 189
Description: Interleukin 8 (IL-8 or chemokine (C-X-C motif) ligand 8, CXCL8) is a chemokine produced by macrophages and other cell types such as epithelial cells, airway smooth muscle cells and endothelial cells. IL-8, also known as neutrophil chemotactic factor, has two primary functions. It induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection. IL-8 also stimulates phagocytosis once they have arrived. IL-8 is also known to be a potent promoter of angiogenesis. In target cells, IL-8 induces a series of physiological responses required for migration and phagocytosis, such as increases in intracellular Ca2+, exocytosis (e.g. histamine release), and the respiratory burst. IL-8 can be secreted by any cells with toll-like receptors that are involved in the innate immune response and has been demonstrated to be a signatory chemokine of CR2+ naive T cells, also known as recent thymic emigrants. Usually, it is the macrophages that see an antigen first, and thus are the first cells to release IL-8 to recruit other cells. Both monomer and homodimer forms of IL-8 have been reported to be potent inducers of the chemokine receptors CXCR1 and CXCR2. The homodimer is more potent, but methylation of Leu25 can block the activity of homodimers.

Anti-IL-8 Antibody

ER1901-61 100ul
EUR 189
Description: IL-8, also known as neutrophil chemotactic factor, has two primary functions. It induces chemotaxis in target cells, primarily neutrophils but also other granulocytes, causing them to migrate toward the site of infection. IL-8 also stimulates phagocytosis once they have arrived. IL-8 is also known to be a potent promoter of angiogenesis. In target cells, IL-8 induces a series of physiological responses required for migration and phagocytosis, such as increases in intracellular Ca2+, exocytosis (e.g. histamine release), and the respiratory burst.IL-8 can be secreted by any cells with toll-like receptors that are involved in the innate immune response. Usually, it is the macrophages that see an antigen first, and thus are the first cells to release IL-8 to recruit other cells. Both monomer and homodimer forms of IL-8 have been reported to be potent inducers of the chemokine receptors CXCR1 and CXCR2. The homodimer is more potent, but methylation of Leu25 can block the activity of homodimers.

Anti-IL-8 Antibody

R1511-15 100ul
EUR 189

Anti-IL-8 Antibody

Y123169 100 µl
EUR 320

Anti-IL-8 antibody

STJ98175 100 µl
EUR 280.8
Description: Mouse monoclonal to IL-8.

Anti-IL-8 antibody

STJ97710 200 µl
EUR 236.4
Description: Mouse monoclonal to IL-8.

Anti-IL-8 antibody

STJ97717 200 µl
EUR 236.4
Description: Mouse monoclonal to IL-8.

Anti-IL-8 antibody

STJ97720 200 µl
EUR 236.4
Description: Mouse monoclonal to IL-8.

anti-IL-8 (3E4D8)

LF-MA30011 100 ul
EUR 448.8
Description: Mouse Monoclonal to IL-8

Anti- Interleukin-8 (IL-8) Antibody

GWB-7ACF57 0.05 mg Ask for price

mAb mouse anti-human IL-8

CT264 0.5 mg
EUR 312

mouse anti-human IL-8 mAb

E409C16-m100 100μL
EUR 395
Description: Available in various conjugation types.

Recombinant Human IL-8 (72a.a.)(rHu IL-8/CXCL8)

701081 25ul
EUR 235
Description: Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human CXCR2 transfected mouse BaF3 cells is less than 2 ng/ml, corresponding to a specific activity of > 5.0 × 105 IU/mg.

Recombinant Human IL-8 (77a.a.)(rHu IL-8/CXCL8)

701082 25ul
EUR 235
Description: Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human CXCR2 transfected mouse BaF3 cells is less than 2 ng/ml, corresponding to a specific activity of > 5.0 × 105 IU/mg.

IL-8/CXCL8, Human

HY-P7224 50ug
EUR 596.4

Human IL-8 Protein

abx060803-25ug 25 ug
EUR 644.4

Human IL-8 Protein

abx060804-25ug 25 ug
EUR 644.4

Human IL-8 protein

PRP1022-100ug 100 μg
EUR 449
Description: Human IL-8 protein, expressed in E. coli

Human IL-8 protein

PRP1022-10ug 10 μg
EUR 59
Description: Human IL-8 protein, expressed in E. coli

Human IL-8 protein

PRP1022-1mg 1 mg
EUR 2609
Description: Human IL-8 protein, expressed in E. coli

Human IL-8 protein

PRP1022-50ug 50 μg
EUR 249
Description: Human IL-8 protein, expressed in E. coli

Human IL-8 Protein

E2RB20061PT 100ul
EUR 485
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Interleukin-8 (IL-8) (72a.a) Human

GWB-3997EC 0.025 mg Ask for price

Recombinant Human IL-8

6487 5 µg
EUR 194

Recombinant Human IL-8

P0180 100ug
EUR 626.83
Description: Recombinant Human protein for IL-8

Recombinant Human IL-8

SJB05-01 25µg/vial
EUR 342

Human Interleukin-8 (IL-8) Antibody (Biotin Conjugate)

13102-05021 150 ug
EUR 229

Rabbit anti-IL-8 Antibody

DL90596A-100ul 100 ul
EUR 270
Description: CXCL8; Interleukin-8; IL-8; C-X-C motif chemokine 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factor

Rabbit anti-IL-8 Antibody

DL90596A-50ul 50 ul
EUR 189
Description: CXCL8; Interleukin-8; IL-8; C-X-C motif chemokine 8; Emoctakin; Granulocyte chemotactic protein 1; GCP-1; Monocyte-derived neutrophil chemotactic factor; MDNCF; Monocyte-derived neutrophil-activating peptide; MONAP; Neutrophil-activating protein 1; NAP-1; Protein 3-10C; T-cell chemotactic factor

Rabbit anti-IL-8 Antibody

YLD4345-100ul 100 ul
EUR 320
Description: Rabbit polyclonal antibody to IL-8

Rabbit anti-IL-8 Antibody

YLD4345-50ul 50 ul
EUR 200
Description: Rabbit polyclonal antibody to IL-8

Anti-IL-8 Monoclonal Antibody

A00423-1 100ul
EUR 476.4
Description: Mouse Monoclonal Antibody for IL-8 Antibody (CXCL8) detection. Tested with IHC in Human, Mouse, Rat.

human DIAplex Human Inflammation - IL-8, IL-17a,

M880130004 1 unit
EUR 650.27

Human IL-8 ELISA antibody pair

CT748-10 10-plate
EUR 656.4

Human IL-8 ELISA antibody pair

CT748-20 20-plate
EUR 1118.4

Anti-swine IL-8 PAb

GWB-OC22N2 1 kit Ask for price

Anti-bovine IL-8 PAb

GWB-03EYX4 100 ug Ask for price

Anti-rabbit IL-8 PAb

GWB-VPE0Z2 1 kit Ask for price

Anti-feline IL-8 PAb

GWB-FEZA83 1 kit Ask for price

Anti-dolphin IL-8 PAb

GWB-KI0031 1 kit Ask for price

Anti-Human IL-8 (I8-S2) Antibody

Y052802 100 µg
EUR 490

Anti-Human IL-17 (CTLA-8) Antibody

101-M783 100 µg
EUR 399
Description: The IL-17 family is comprised of at least six proinflammatory cytokines that share a conserved cysteine-knot structure but diverge at the N-terminus. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. IL-17F is the most homologous to IL-17, but is induced only by IL-23 in activated monocytes. IL-17B binds the IL-17B receptor, but not the IL-17 receptor; it is most homologous with IL-17D, which is expressed by resting CD4+ T cells and CD19+ B cells. IL-17E is mainly produced by Th2 cells and recruits eosinophils to lung tissue. IL-17C has a very restricted expression pattern but has been detected in adult prostate and fetal kidney libraries.

Mouse Monoclonal anti-Human IL-8 Antibody

xAP-0435 100ug
EUR 280

Mouse Monoclonal anti-Human IL-8 Antibody

xAP-0436 100ug
EUR 280

Mouse Monoclonal anti-Human IL-8 Antibody

xAP-0437 100ug
EUR 280

Anti-Human IL-8 Rabbit Polyclonal Antibody

TA328221 100 µg Ask for price

Human Interleukin 8 (IL-8) CLIA Kit

abx195916-96tests 96 tests
EUR 990

Human IL-8 -Interleukin 8- CLIA Kit

E-CL-H0048-24Tests 24 Tests
EUR 180
Description: Sandwich

Human IL-8 -Interleukin 8- CLIA Kit

E-CL-H0048-48Tests 48 Tests
EUR 546
Description: Sandwich

Human IL-8 -Interleukin 8- CLIA Kit

E-CL-H0048-96Tests 96 Tests
EUR 682
Description: Sandwich

Human IL-8 -Interleukin 8- CLIA Kit

E-CL-H0048-96Tests10 96 Tests *10
EUR 6820
Description: Sandwich

Human IL-8 -Interleukin 8- CLIA Kit

E-CL-H0048-96Tests5 96 Tests *5
EUR 3410
Description: Sandwich

mouse anti-human IL-8 mAb(Q10)

E4A09D07-Q10 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

mouse anti-human IL-8 mAb(Q36)

E4A09D07-Q36 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Rabbit anti-Human IL-8 mAb (CAP)

RM17646 100μg Ask for price

Rabbit anti-Human IL-8 mAb (DET)

RM17647 100μg Ask for price

Rabbit anti-Human IL-8 mAb (CAP)

RM17648 100μg Ask for price

Rabbit anti-Human IL-8 mAb (DET)

RM17649 100μg Ask for price

Human Interleukin 8,IL-8 ELISA KIT

201-12-0090 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human IL-8(Interleukin 8) ELISA Kit

EH0205 96T
EUR 571.5
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human IL-8(Interleukin 8) ELISA Kit

EKF57074-48T 48T
EUR 396.9

Human IL-8(Interleukin 8) ELISA Kit

EKF57074-5x96T 5x96T
EUR 2693.25

Human IL-8(Interleukin 8) ELISA Kit

EKF57074-96T 96T
EUR 567

Human IL-8 (Interleukin 8) ELISA Kit

EKE60046-5x96T 5x96T
EUR 2667.6

Human IL-8 (Interleukin 8) ELISA Kit

EKE60046-96T 96T
EUR 561.6

Human Interleukin 8,IL-8 ELISA KIT

EKC40086-48T 48T
EUR 328.86

Human Interleukin 8,IL-8 ELISA KIT

EKC40086-5x96T 5x96T
EUR 2231.55

Human Interleukin 8,IL-8 ELISA KIT

EKC40086-96T 96T
EUR 469.8

Human Interleukin 8(IL-8) Elisa Kit

EK710269 96 Wells
EUR 0.77

Human IL-8(Interleukin 8) ELISA Kit

E39EH0205 96T
EUR 595

Human Interleukin 8(IL-8) Elisa Kit

EK610269 96 Wells
EUR 0.1

Human Interleukin 8,IL-8 ELISA KIT

EK0240 96 tests
EUR 659

Human Interleukin 8 (IL-8) ELISA Kit

EK10257 96Т
EUR 799

Human Interleukin 8 (IL-8) ELISA Kit

AE38177HU-48Tests 48 Tests
EUR 200
Description: Human (Homo sapiens)

Human Interleukin 8 (IL-8) ELISA Kit

AE38177HU-96Tests 96 Tests
EUR 360
Description: Human (Homo sapiens)

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