Parameter identifiability evaluation and visualization in large-scale kinetic fashions of biosystems.

BACKGROUND

Kinetic fashions of biochemical methods normally include odd differential equations which have many unknown parameters. A few of these parameters are sometimes virtually unidentifiable, that’s, their values can’t be uniquely decided from the out there knowledge.

Attainable causes are lack of affect on the measured outputs, interdependence amongst parameters, and poor knowledge high quality. Uncorrelated parameters might be seen as the important thing tuning knobs of a predictive mannequin. Due to this fact, earlier than making an attempt to carry out parameter estimation (mannequin calibration) it is very important characterize the subset(s) of identifiable parameters and their interaction. As soon as that is achieved, it’s nonetheless essential to carry out parameter estimation, which poses further challenges.

METHODS

We current a technique that (i) detects high-order relationships amongst parameters, and (ii) visualizes the outcomes to facilitate additional evaluation. We use a collinearity index to quantify the correlation between parameters in a gaggle in a computationally environment friendly method. Then we apply integer optimization to search out the biggest teams of uncorrelated parameters. We additionally use the collinearity index to establish small teams of extremely correlated parameters. The outcomes recordsdata might be visualized utilizing Cytoscape, exhibiting the identifiable and non-identifiable teams of parameters along with the mannequin construction in the identical graph.

RESULTS

Our contributions alleviate the difficulties that seem at totally different levels of the identifiability evaluation and parameter estimation course of. We present easy methods to mix world optimization and regularization methods for calibrating medium and huge scale organic fashions with average computation occasions.

Then we consider the sensible identifiability of the estimated parameters utilizing the proposed methodology. The identifiability evaluation methods are applied as a MATLAB toolbox known as VisId, which is freely out there as open supply from GitHub ( https://github.com/gabora/visid ).

CONCLUSIONS

Our strategy is geared in the direction of scalability. It permits the sensible identifiability evaluation of dynamic fashions of enormous dimension, and accelerates their calibration. The visualization device permits modellers to detect elements which might be problematic and want refinement or reformulation, and offers experimentalists with info that may be useful within the design of recent experiments.

Validation of the Utilized Biosystems RapidFinder Shiga Toxin-Producing E. coli (STEC) Detection Workflow.

The Utilized Biosystems™ RapidFinder™ STEC Detection Workflow (Thermo Fisher Scientific) is a whole protocol for the speedy qualitative detection of Escherichia coli (E. coli) O157:H7 and the “Huge 6” non-O157 Shiga-like toxin-producing E. coli (STEC) serotypes (outlined as serogroups: O26, O45, O103, O111, O121, and O145).

The RapidFinder STEC Detection Workflow makes use of both the automated preparation of PCR-ready DNA utilizing the Utilized Biosystems PrepSEQ™ Nucleic Acid Extraction Package along side the Utilized Biosystems MagMAX™ Specific 96-well magnetic particle processor or the Utilized Biosystems PrepSEQ Speedy Spin equipment for handbook preparation of PCR-ready DNA.

Two separate assays comprise the RapidFinder STEC Detection Workflow, the Utilized Biosystems RapidFinder STEC Screening Assay and the Utilized Biosystems RapidFinder STEC Affirmation Assay. The RapidFinder STEC Screening Assay contains primers and probes to detect the presence of stx1 (Shiga toxin 1), stx2 (Shiga toxin 2), eae (intimin), and E. coli O157 gene targets. The RapidFinder STEC Affirmation Assay contains primers and probes for the “Huge 6″ non-O157 STEC and E. coli O157:H7. Using these two assays in tandem permits a person to detect precisely the presence of the “Huge 6” STECs and E. coli O157:H7. The efficiency of the RapidFinder STEC Detection Workflow was evaluated in a technique comparability research, in inclusivity and exclusivity research, and in a robustness analysis.

The assays had been in comparison with the U.S. Division of Agriculture (USDA), Meals Security and Inspection Service (FSIS) Microbiology Laboratory Guidebook (MLG) 5.09: Detection, Isolation and Identification of Escherichia coli O157:H7 from Meat Merchandise and Carcass and Environmental Sponges for uncooked floor beef (73% lean) and USDA/FSIS-MLG 5B.05: Detection, Isolation and Identification of Escherichia coli non-O157:H7 from Meat Merchandise and Carcass and Environmental Sponges for uncooked beef trim. No statistically important variations had been noticed between the reference methodology and the person or mixed kits forming the candidate assay utilizing both of the DNA preparation kits (handbook or automated extraction). For the inclusivity and exclusivity analysis, the RapidFinder STEC Detection Workflow, comprising each RapidFinder STEC screening and affirmation kits, accurately recognized all 50 goal organism isolates and accurately excluded all 30 nontarget strains for each of the assays evaluated.

The outcomes of those research reveal the sensitivity and selectivity of the RapidFinder STEC Detection Workflow for the detection of E. coli O157:H7 and the “Huge 6” STEC serotypes in each uncooked floor beef and beef trim. The robustness testing demonstrated that minor variations within the methodology parameters didn’t influence the accuracy of the assay and highlighted the significance of following the right incubation temperatures.

uwmembraneproteins
uwmembraneproteins

Human CXCL7 Antibody

32852-05111 150 ug
EUR 261.00

CXCL7/NAP-2

PR27118 2 ug
EUR 191.00

Mouse PPBP/CXCL7 PicoKine ELISA Kit

EK0730 96 wells
EUR 425.00
Description: For Quantitative Detection of mouse CXCL7 in cell culture supernates, serum and plasma (heparin, EDTA).

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280.00

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280.00

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280.00

CXCL7 ELISA KIT|Human

EF001450 96 Tests
EUR 689.00

NAP-2/CXCL7, Human

HY-P7268 50ug
EUR 533.00

NAP-2/CXCL7, Rat

HY-P7269 50ug
EUR 533.00

Human CXCL7 ELISA Kit

LF-EK50893 1×96T
EUR 648.00

NAP-2, CXCL7, human

RC312-18 2ug
EUR 104.38
  • Product category: Proteins/Recombinant Proteins/Cytokines

NAP-2, CXCL7, rat

RC352-18 2ug
EUR 104.38
  • Product category: Proteins/Recombinant Proteins/Cytokines

Mouse beta Thromboglobulin (CXCL7/bTG) CLIA Kit

20-abx491403
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 0
  • 1
  • 2
  • Please enquire.

ELISA kit for Human CXCL7

EK5304 96 tests
EUR 553.00
Description: Enzyme-linked immunosorbent assay kit for quantification of Human CXCL7 in samples from serum, plasma, tissue homogenates and other biological fluids.

Human CXCL7 PicoKine ELISA Kit

EK0729 96 wells
EUR 425.00
Description: For quantitative detection of human CXCL7 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human CXCL7 AssayMax ELISA Kit

EC2270-1 96 Well Plate
EUR 477.00

Human CXCL7 Antibody (Biotin Conjugate)

32852-05121 150 ug
EUR 369.00

Rat PPBP/CXCL7 PicoKine ELISA Kit

EK0731 96 wells
EUR 425.00
Description: For Quantitative Detection of rat CXCL7 in cell culture supernates, serum and plasma (heparin, EDTA).

NAP-2/CXCL7 (CHO-expressed), Human

HY-P7267 50ug
EUR 497.00

ThymusChemokine‑1/CXCL7 (CHO-expressed), Rat

HY-P7301 10ug
EUR 291.00

Neutrophil Activating Protein-2 (CXCL7) Antibody

20-abx137035
  • EUR 356.00
  • EUR 523.00
  • 0
  • 1
  • Shipped within 5-10 working days.

Neutrophil Activating Protein-2 (CXCL7) Protein

20-abx261559
  • EUR 328.00
  • EUR 3418.00
  • EUR 230.00
  • 0
  • 1
  • 2
  • Shipped within 5-10 working days.

Neutrophil Activating Protein-2 (CXCL7) Protein

20-abx261561
  • EUR 328.00
  • EUR 3418.00
  • EUR 230.00
  • 0
  • 1
  • 2
  • Shipped within 5-10 working days.

Human CXCL7 AssayLite Antibody (FITC Conjugate)

32852-05141 150 ug
EUR 428.00

Human CXCL7 AssayLite Antibody (RPE Conjugate)

32852-05151 150 ug
EUR 428.00

Human CXCL7 AssayLite Antibody (APC Conjugate)

32852-05161 150 ug
EUR 428.00

Human CXCL7 AssayLite Antibody (PerCP Conjugate)

32852-05171 150 ug
EUR 471.00

Recombinant Human CXCL7/NAP-2 Protein

RP00829 10 μg
EUR 221.00

Human CXCL7(Platelet basic protein) ELISA Kit

EH0007 96T
EUR 567.60
  • Detection range: 15.6-1000 pg/ml
  • Uniprot ID: P02775
  • Alias: CXCL7/CTAP III/NAP-2/PPBP/connective tissue-activating peptide III/CTAP3CTAP-III/CTAPIII/CXC chemokine ligand 7/C-X-C motif chemokine 7/CXCL7b-TG1/LA-PF4/LDGFTC1/Leukocyte-derived growth fact
  • Show more
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Recombinant Human Neutrophil Activating Protein-2 (CXCL7)

7-02059 2µg Ask for price

Recombinant Human Neutrophil Activating Protein-2 (CXCL7)

7-02060 10µg Ask for price

Recombinant Human Neutrophil Activating Protein-2 (CXCL7)

7-02061 1mg Ask for price

Recombinant Rat Neutrophil Activating Protein-2 (CXCL7)

7-02065 2µg Ask for price

Recombinant Rat Neutrophil Activating Protein-2 (CXCL7)

7-02066 10µg Ask for price

Recombinant Rat Neutrophil Activating Protein-2 (CXCL7)

7-02067 1mg Ask for price

ELISA kit for Mouse ?TG/PBP/CXCL7/NAP2 (Thromboglobulin, Beta)

E-EL-M1269 1 plate of 96 wells
EUR 534.00
  • Gentaur's ?TG/PBP/CXCL7/NAP2 ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse ?TG/PBP/CXCL7/NAP2. Standards or samples are added to the micro ELISA plat
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Mouse ?TG/PBP/CXCL7/NAP2 (Thromboglobulin, Beta) in samples from Serum, Plasma, Cell supernatant

Pig Platelet Basic Protein / CXCL7 (PPBP) ELISA Kit

abx511493-96tests 96 tests
EUR 911.00
  • Shipped within 5-12 working days.

Neutrophil Activating Protein-2 (CXCL7), 95 a.a. Protein

20-abx260678
  • EUR 328.00
  • EUR 3418.00
  • EUR 230.00
  • 0
  • 1
  • 2
  • Shipped within 5-10 working days.

Rat Platelet Basic Protein / CXCL7 (PPBP) ELISA Kit

abx255841-96tests 96 tests
EUR 668.00
  • Shipped within 5-12 working days.

Human Platelet Basic Protein / CXCL7 (PPBP) ELISA Kit

abx252283-96tests 96 tests
EUR 668.00
  • Shipped within 5-12 working days.

Recombinant (E.Coli) Human Neutrophil Activating Protein-2 (CXCL7)

RP-1008 10 ug
EUR 286.00

Human Thromboglobulin, Beta (bTG/PBP/CXCL7/NAP2) CLIA Kit

abx197774-96tests 96 tests
EUR 825.00
  • Shipped within 5-12 working days.

Recombinant Human Neutrophil Activating Protein-2 (CXCL7), 95 a.a.

7-02062 2µg Ask for price

Recombinant Human Neutrophil Activating Protein-2 (CXCL7), 95 a.a.

7-02063 10µg Ask for price

Recombinant Human Neutrophil Activating Protein-2 (CXCL7), 95 a.a.

7-02064 1mg Ask for price

Human CXCL7 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

EZ0729 5 plates/kit
EUR 268.00
Description: For the development of sandwich ELISA kit to measure human CXCL7 in cell culture supernates, cell lysates, tissue homogenates, serum and plasma (heparin, EDTA).

ELISA kit for Rat ?TG/PBP/CXCL7/NAP2 (Thromboglobulin, Beta)

E-EL-R1087 1 plate of 96 wells
EUR 534.00
  • Gentaur's ?TG/PBP/CXCL7/NAP2 ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Rat ?TG/PBP/CXCL7/NAP2. Standards or samples are added to the micro ELISA plate
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Rat ?TG/PBP/CXCL7/NAP2 (Thromboglobulin, Beta) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human ?TG/PBP/CXCL7/NAP2 (Thromboglobulin, Beta)

E-EL-H1007 1 plate of 96 wells
EUR 534.00
  • Gentaur's ?TG/PBP/CXCL7/NAP2 ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Human ?TG/PBP/CXCL7/NAP2. Standards or samples are added to the micro ELISA plat
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Human ?TG/PBP/CXCL7/NAP2 (Thromboglobulin, Beta) in samples from Plasma

NAP-2 Neutrophil Activating Protein-2 Human Recombinant Protein (CXCL7)

PROTP02775 Regular: 10ug
EUR 317.00
Description: Neutrophil Activating Protein-2 Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 70 amino acids and having a molecular mass of 7609 Dalton. ;The NAP-2 is purified by proprietary chromatographic techniques.

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, GST, E.coli-100ug

QP8641-ec-100ug 100ug
EUR 408.00

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, GST, E.coli-10ug

QP8641-ec-10ug 10ug
EUR 200.00

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, GST, E.coli-1mg

QP8641-ec-1mg 1mg
EUR 1632.00

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, GST, E.coli-200ug

QP8641-ec-200ug 200ug
EUR 634.00

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, GST, E.coli-500ug

QP8641-ec-500ug 500ug
EUR 1060.00

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, GST, E.coli-50ug

QP8641-ec-50ug 50ug
EUR 263.00

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-100ug

QP10212-ec-100ug 100ug
EUR 988.00

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-10ug

QP10212-ec-10ug 10ug
EUR 290.00

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-250ug

QP10212-ec-250ug 250ug
EUR 1731.00

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-2ug

QP10212-ec-2ug 2ug
EUR 154.00

Recombinant Rat NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-100ug

QP10285-ec-100ug 100ug
EUR 1178.00

Recombinant Rat NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-10ug

QP10285-ec-10ug 10ug
EUR 290.00

Recombinant Rat NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-250ug

QP10285-ec-250ug 250ug
EUR 2067.00

Recombinant Rat NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-2ug

QP10285-ec-2ug 2ug
EUR 154.00

NAP-2 Neutrophil Activating Protein-2 Rat Recombinant Protein (CXCL7)

PROTQ99ME0 Regular: 10ug
EUR 317.00
Description: NAP-2 Rat Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 62 amino acids and having a molecular mass of 6.8kDa.;The NAP 2 is purified by proprietary chromatographic techniques.

Recombinant Human C-X-C Motif Chemokine 7/CXCL7/NAP-2

C056-10ug 10ug
EUR 202.00
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human C-X-C Motif Chemokine 7/CXCL7/NAP-2

C056-1mg 1mg
EUR 2283.00
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human C-X-C Motif Chemokine 7/CXCL7/NAP-2

C056-500ug 500ug
EUR 1613.00
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human C-X-C Motif Chemokine 7/CXCL7/NAP-2

C056-50ug 50ug
EUR 496.00
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

NAP-2-95 Neutrophil Activating Protein-2 (CXCL7) Human Recombinant Protein, 95 a.a.

PROTP02775-1 Regular: 10ug
EUR 317.00
Description: NAP 2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 95 amino acids (35-128) and having a molecular mass of 10.3 kDa.;The NAP 2 is purified by proprietary chromatographic techniques.

anti-mouse VLK

AR03-PA0002 100 ul
EUR 334.00
Description: Rabbit polyclonal to VLK

UltraTek Anti-Mouse

ABJ008 8 ml
EUR 80.00

UltraTek Anti-Mouse

ABJ015 15 ml
EUR 98.00

UltraTek Anti-Mouse

ABJ125 125 ml
EUR 228.00

UltraTek Anti-Mouse

ABJ500 500 ml
EUR 554.00

UltraTek Anti-Mouse

ABJ999 1000 ml
EUR 934.00

SensiTek Anti-Mouse

ABC008 8 ml
EUR 71.00

SensiTek Anti-Mouse

ABC015 15 ml
EUR 80.00

SensiTek Anti-Mouse

ABC125 125 ml
EUR 176.00

SensiTek Anti-Mouse

ABC500 500 ml
EUR 420.00

SensiTek Anti-Mouse

ABC999 1000 ml
EUR 711.00

Mouse anti IgA1

10-I06A 1 mg
EUR 308.00
Description: Mouse anti IgA1 antibody

Mouse Anti-FcεRIα

MOFCeRIaAP(V100) 100 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaAP(V25) 25 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaB(V100) 100 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaB(V25) 25 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaCFB(V100) 100 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaCFB(V25) 25 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaF(V100) 100 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaF(V25) 25 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaF(V500) 500 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaPE(V100) 100 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaPE(V25) 25 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaPP(V100) 100 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaPP(V25) 25 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaPP55(V100) 100 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaPP55(V25) 25 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaPU(V100) 100 ug
EUR 50.00

Mouse Anti-FcεRIα

MOFCeRIaPU(V500) 500 ug
EUR 50.00

Mouse Anti-IL2

MOIL2A(V100) 100 ug
EUR 50.00

Mouse Anti-IL2

MOIL2A(V25) 25 ug
EUR 50.00

Mouse Anti-IL2

MOIL2B(V100) 100 ug
EUR 50.00

Mouse Anti-IL2

MOIL2B(V25) 25 ug
EUR 50.00

Mouse Anti-IL2

MOIL2CFB(V100) 100 ug
EUR 50.00

Mouse Anti-IL2

MOIL2CFB(V25) 25 ug
EUR 50.00

Mouse Anti-IL2

MOIL2F(V100) 100 ug
EUR 50.00

Mouse Anti-IL2

MOIL2F(V25) 25 ug
EUR 50.00

Mouse Anti-IL2

MOIL2F(V500) 500 ug
EUR 50.00

Mouse Anti-IL2

MOIL2PE(V100) 100 ug
EUR 50.00

Mouse Anti-IL2

MOIL2PE(V25) 25 ug
EUR 50.00

Mouse Anti-IL2

MOIL2PP(V100) 100 ug
EUR 50.00

Mouse Anti-IL2

MOIL2PP(V25) 25 ug
EUR 50.00

Mouse Anti-IL2

MOIL2PP5.5(V100) 100 ug
EUR 50.00

Mouse Anti-IL2

MOIL2PP5.5(V25) 25 ug
EUR 50.00

Mouse Anti-IL2

MOIL2PU(V100) 100 ug
EUR 50.00

Mouse Anti-IL2

MOIL2PU(V500) 500 ug
EUR 50.00

Mouse Anti-IL4

MOIL4A(V100) 100 ug
EUR 50.00

Mouse Anti-IL4

MOIL4A(V25) 25 ug
EUR 50.00

Mouse Anti-IL4

MOIL4B(V100) 100 ug
EUR 50.00

Mouse Anti-IL4

MOIL4B(V25) 25 ug
EUR 50.00

Mouse Anti-IL4

MOIL4CFB(V100) 100 ug
EUR 50.00

Mouse Anti-IL4

MOIL4CFB(V25) 25 ug
EUR 50.00

Mouse Anti-IL4

MOIL4F(V100) 100 ug
EUR 50.00

Mouse Anti-IL4

MOIL4F(V25) 25 ug
EUR 50.00

Mouse Anti-IL4

MOIL4F(V500) 500 ug
EUR 50.00

Mouse Anti-IL4

MOIL4PE(V100) 100 ug
EUR 50.00

Mouse Anti-IL4

MOIL4PE(V25) 25 ug
EUR 50.00

Mouse Anti-IL4

MOIL4PP(V100) 100 ug
EUR 50.00

Mouse Anti-IL4

MOIL4PP(V25) 25 ug
EUR 50.00

Mouse Anti-IL4

MOIL4PP5.5(V100) 100 ug
EUR 50.00

Mouse Anti-IL4

MOIL4PP5.5(V25) 25 ug
EUR 50.00

Mouse Anti-IL4

MOIL4PU(V100) 100 ug
EUR 50.00

Mouse Anti-IL4

MOIL4PU(V500) 500 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRA(V100) 100 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRA(V25) 25 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRB(V100) 100 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRB(V25) 25 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRCFB(V100) 100 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRCFB(V25) 25 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRF(V100) 100 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRF(V25) 25 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRF(V500) 500 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRPE(V100) 100 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRPE(V25) 25 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRPP(V100) 100 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRPP(V25) 25 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRPP5.5(V100) 100 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRPP5.5(V25) 25 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRPU(V100) 100 ug
EUR 50.00

Mouse Anti-KLRG1

MOKLRPU(V500) 500 ug
EUR 50.00

Anti-Procalcitonin antibody *Mouse anti-human, monoclonal *

V100125 50 ug
EUR 306.00
  • R-phrase:
  • H-Phrase:
  • Symbol for dangerous compounds:
  • UNSPEC Code:

Anti-Procalcitonin antibody *Mouse anti-human, monoclonal *

V100126 1 mg
EUR 393.00
  • R-phrase:
  • H-Phrase:
  • Symbol for dangerous compounds:
  • UNSPEC Code:

Monoclonal Mouse Anti-HCV

C010117-10mg 10mg
EUR 5170.00

Monoclonal Mouse Anti-HCV

C010117-1mg 1mg
EUR 776.00

Monoclonal Mouse Anti-BSA

C010118-10mg 10mg
EUR 1368.00

Monoclonal Mouse Anti-BSA

C010118-1mg 1mg
EUR 269.00

Mouse Anti Human IgM

E61I00402 100ug
EUR 343.00

Goat Anti Mouse IgG

E61I00501 100ug
EUR 343.00

Rabbit anti mouse IgG

E61I00901 100ug
EUR 343.00

Mouse anti RBC IgG

E61I01101 10mg
EUR 343.00

Mouse Anti FITC Antibody

E61I01401 100ug
EUR 343.00

Mouse Anti KLH McAb

E61I01501 100ug
EUR 343.00

Mouse anti human IgA

E61I02101 100ug
EUR 343.00

Mouse anti human IgE

E61I02201 100ug
EUR 343.00

anti- HBsAg mouse antibody

HBV001 100µg
EUR 548.75
  • Immunogen: HBsAg
  • Research Area: Signal Transduction
Description: Antibody raised against HBsAg mouse

anti- HBsAg mouse antibody

HBV002 100µg
EUR 548.75
  • Immunogen: HBsAg
  • Research Area: Signal Transduction
Description: Antibody raised against HBsAg mouse

Rabbit anti- mouse IgA

FNab09894 100µg
EUR 548.75
  • Recommended dilution: WB: 1:1000-1:10000
  • IHC: 1:2000-1:20000
  • Immunogen: mouse IgA
  • Research Area: Immunology
Description: Antibody raised against Rabbit mouse IgA

Goat Anti-Mouse FC

FNSA-0002 500 uL
EUR 428.40
  • Suggested dilution: 1:2000-1:10000 for western blotting with ECL substrates1:1000-1:20000 for ELISA and Western blotting with chromogenic substrates
  • Stabilizer: 5mg/ml BSA ( IgG-Free, Protease-Free)
Description: Goat Anti-Mouse FC secondary antibody

Goat anti Mouse IgG1

FNSA-0086 500 uL
EUR 306.60
  • Suggested dilution: 1:2000-1:10000 for western blotting with ECL substrates1:1000-1:20000 for ELISA and Western blotting with chromogenic substrates
  • Stabilizer: 5mg/ml BSA ( IgG-Free, Protease-Free)
Description: Goat anti Mouse IgG1 secondary antibody

Validation of the Utilized Biosystems 7500 Quick Instrument for Detection of Listeria monocytogenes with the SureTect Listeria monocytogenes PCR Assay.

In 2013, the Thermo Scientific™ SureTect™ Listeria monocytogenes Actual-Time PCR Assay was licensed by the AOAC Analysis Institute (RI) Efficiency Examined Strategies(SM) program as a speedy methodology for the detection of L. monocytogenes from a variety of meals matrixes and floor samples.

This report particulars the tactic modification research undertaken to increase the evaluation of this PCR assay to the Utilized Biosystems™ 7500 Quick PCR Instrument and Utilized Biosystems RapidFinder™ Specific 2.zero software permitting the usage of the SureTect assay on a 96 effectively format PCR cycler along with the present workflow, which makes use of the 24 effectively Thermo Scientific PikoReal™ PCR Instrument and Thermo Scientific SureTect software program.

As a result of this research was deemed by AOAC-RI to be a degree 2 methodology modification research, a consultant vary of meals matrixes overlaying uncooked floor turkey, 2% fats pasteurized milk, and bagged lettuce in addition to chrome steel floor samples had been analyzed with the Utilized Biosystems 7500 Quick PCR Instrument and RapidFinder Specific 2.zero software program.

All testing was carried out compared to the reference methodology detailed in Worldwide Group for Standardization (ISO) 6579:2002. No important distinction by likelihood of detection statistical evaluation was discovered between the SureTect Listeria monocytogenes PCR Assay or the ISO reference methodology strategies for any of the matrixes analyzed throughout the research.

Validation of the Utilized Biosystems 7500 Quick Instrument for the Detection of Salmonellae with SureTect Salmonella Species PCR Package.

The Thermo Scientific SureTect™ Salmonella species real-time PCR assay is a speedy various methodology designed for the detection of salmonellae in a variety of meals, animal feeds, and production-environment samples. The assay has beforehand been validated in accordance with the AOAC Analysis Institute Efficiency Examined Strategies(SM) program utilizing Thermo Scientific PikoReal PCR cycler and Thermo Scientific SureTect Software program Efficiency Examined Methodology 051303).

This report particulars the method-modification research carried out to validate an up to date assay format, using a diminished goal probe focus and an extension of the PCR cycler platform to allow the usage of the equipment with a Utilized Biosystems 7500 Quick PCR cycler and Utilized Biosystems RapidFinder™ Specific 2.zero software program.

Throughout this validation research, a matrix research was carried out on a subset of the tactic’s claimed matrixes, evaluating the efficiency of the modified SureTect Salmonella species equipment (a diminished goal probe focus with a 7500 Quick platform) to the reference methodology detailed in ISO 6579:2002.

No important distinction by likelihood of detection statistical evaluation was discovered between SureTect or Worldwide Group for Standardization strategies for any of the matrixes analyzed throughout the research. Inclusivity and exclusivity research utilizing the modified methodology demonstrated correct outcomes for the 117 Salmonella and 36 non-Salmonella strains examined. A number of manufacturing plenty of the newly formatted equipment had been evaluated and located to be in step with the present assay. Robustness research confirmed that the change to the equipment had no influence on the assay’s efficiency when alterations had been made to methodology parameters having the best potential influence on assay efficiency.

Human Insulin Like Growth Factor 1 (IGF-1) ELISA Kit, 96 tests, quantitative

100-600-IGF 1 kit
EUR 712.00

Mouse Insulin Like Growth Factor 1 (IGF-1) ELISA Kit, 96 tests, quantitative

100-605-IGF 1 kit
EUR 712.00

Rat Insulin Like Growth Factor 1 (IGF-1) ELISA Kit, 96 tests, quantitative

100-610-IGF 1 kit
EUR 712.00

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349.00

Anti-IGF-IR antibody

STJ93647 200 µl
EUR 197.00
Description: IGF-IR is a protein encoded by the IGF1R gene which is approximately 154,7 kDa. IGF-IR is localised to the cell membrane. It is involved in apoptotic pathways, the GPCR pathway and ERK signalling. It is a receptor tyrosine kinase which mediates actions of insulin-like growth factor 1. The activated protein is involved in cell growth and survival control and is also crucial for tumour transformation and survival of malignant cells. It is formed from two subunits, each of which is comprised of an extracellular alpha-subunit and a transmembrane beta-subunit with intracellular tyrosine kinase activity. IGF-IR is expressed in the nervous system, skin, pancreas, lung and muscle. Mutations in the IGF1R gene may result in insulin-like growth factor 1 resistance. STJ93647 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of IGF-IR protein.

Anti-IGF-IR antibody

STJ93648 200 µl
EUR 197.00
Description: Rabbit polyclonal to IGF-IR.

Anti-IGF-I antibody

STJ93653 200 µl
EUR 197.00
Description: Rabbit polyclonal to IGF-I.

Anti-IGF-IIR antibody

STJ93654 200 µl
EUR 197.00
Description: Rabbit polyclonal to IGF-IIR.

Anti-IGF-IIR antibody

STJ93655 200 µl
EUR 197.00
Description: Rabbit polyclonal to IGF-IIR.

Anti-IGF-IR antibody

STJ93656 200 µl
EUR 197.00
Description: Rabbit polyclonal to IGF-IR.

Anti-IGF-IR antibody

STJ93657 200 µl
EUR 197.00
Description: Rabbit polyclonal to IGF-IR.

Anti-IGF-IIR antibody

STJ96634 200 µl
EUR 197.00
Description: Rabbit polyclonal to IGF-IIR.

Anti-IGF-IR antibody

STJ98158 100 µl
EUR 234.00
Description: Mouse monoclonal to IGF-IR.

Anti-IGF-IR antibody

STJ98159 100 µl
EUR 234.00
Description: Mouse monoclonal to IGF-IR.

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280.00

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280.00

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280.00

Anti-Rat IGF-1 Antibody

5121-100
EUR 316.00

Anti-Rat IGF-1 Antibody

5121-30T
EUR 146.00

anti-IGF-1R (Ab-1280)

LF-PA20229 100 ul
EUR 334.00
Description: Rabbit polyclonal to IGF-1R

anti-IGF-1R (Ab-1346)

LF-PA20230 100 ul
EUR 334.00
Description: Rabbit polyclonal to IGF-1R

anti-IGF-1R (Ab-1161)

LF-PA20231 100 ul
EUR 334.00
Description: Rabbit polyclonal to IGF-1R

anti-IGF-1R (Phospho-Tyr1161)

LF-PA20233 100 ul
EUR 354.00
Description: Rabbit polyclonal to IGF-1R (Phospho-Tyr1161)

Human Salivary IGF(salivary IGF) ELISA Kit

QY-E05383 96T
EUR 361.00

IGF-1, Human

HY-P7018 10ug
EUR 108.00

IGF-2, Human

HY-P7019 100ug
EUR 360.00

IGF-BP3, Human

HY-P7020 10ug
EUR 234.00

IGF-BP5, Human

HY-P7021 50ug
EUR 601.00

IGF-1, human

RC216-12 1mg
EUR 376.25
  • Product category: Proteins/Recombinant Proteins/Growth Factors

IGF-BP3, human

RC216-12B3 5ug
EUR 104.38
  • Product category: Proteins/Recombinant Proteins/Growth Factors

Polyclonal Anti-Rat IGF-1 Antibody

APR00269G 0.1mg
EUR 484.00
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Anti-Rat IGF-1 . This antibody is tested and proven to work in the following applications:

Anti-IGF-1R (Ab-1161) Antibody

A00070-1 100ul
EUR 397.00
Description: Rabbit Polyclonal IGF-1R (Ab-1161) Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

anti-IGF-1R (Ab-1165/1166)

LF-PA20232 100 ul
EUR 334.00
Description: Rabbit polyclonal to IGF-1R

anti-IGF-1R (Phospho-Tyr1165/Tyr1166)

LF-PA20234 100 ul
EUR 354.00
Description: Rabbit polyclonal to IGF-1R (Phospho-Tyr1165/Tyr1166)

Anti-Phospho-IGF-IR (Y1161) antibody

STJ90298 200 µl
EUR 197.00
Description: Rabbit polyclonal to Phospho-IGF-IR (Y1161).

Anti-Phospho-IGF-IIR (S2409) antibody

STJ90923 200 µl
EUR 197.00
Description: Rabbit polyclonal to Phospho-IGF-IIR (S2409).

Anti-Phospho-IGF-IR (Y1161) antibody

STJ91026 200 µl
EUR 197.00
Description: Rabbit polyclonal to Phospho-IGF-IR (Y1161).

Anti-Phospho-IGF-IR (Y1346) antibody

STJ91187 200 µl
EUR 197.00
Description: Rabbit polyclonal to Phospho-IGF-IR (Y1346).

IGF-II

PR15045CF 50 ug
EUR 278.00

IGF-BP1, human recombinant

4717-100
EUR 620.00

IGF-BP1, human recombinant

4717-1000
EUR 3149.00

IGF-BP1, human recombinant

4717-25
EUR 256.00

IGF-BP3, human recombinant

4720-100
EUR 620.00

IGF-BP3, human recombinant

4720-1000
EUR 3149.00

IGF-BP3, human recombinant

4720-25
EUR 256.00

IGF-BP5, human recombinant

4723-100
EUR 620.00

IGF-BP5, human recombinant

4723-1000
EUR 3149.00

IGF-BP5, human recombinant

4723-25
EUR 256.00

IGF-I, human recombinant

4119-100
EUR 175.00

IGF-I, human recombinant

4119-1000
EUR 343.00

IGF-I, human recombinant

4119-10MG
EUR 1529.00

IGF-I, human recombinant

4119-1G
EUR 41157.00

IGF-I, human recombinant

4119-20MG
EUR 2328.00

IGF-I, human recombinant

4119-5000
EUR 958.00

IGF-I, human recombinant

4119-50MG
EUR 4220.00

IGF-II, human recombinant

4122-10
EUR 137.00

IGF-II, human recombinant

4122-1000
EUR 1572.00

IGF-II, human recombinant

4122-50
EUR 256.00

Biotinyl Human IGF-I

AQU010 10 µg
EUR 253.00

Biotinyl Human IGF-I

AQU050 50 µg
EUR 346.00

Biotinyl Human IGF-I

AQU100 100 µg
EUR 531.00

Biotinyl Human IGF-I

AQU500 500 µg
EUR 1088.00

IGF-BP2, human recombinant

7165-10
EUR 251.00

IGF-BP2, human recombinant

7165-50
EUR 936.00

IGF-BP7, human recombinant

7167-10
EUR 207.00

IGF-BP7, human recombinant

7167-50
EUR 675.00

IGF-BP6, human recombinant

7350-20
EUR 370.00

Human IGF-I Protein

abx060791-100ug 100 ug
EUR 467.00
  • Shipped within 5-10 working days.

Human [Ala31] IGF-I

AIU020 20 µg
EUR 253.00

Human [Ala31] IGF-I

AIU100 100 µg
EUR 346.00

Human [Leu60] IGF-I

ABU020 20 µg
EUR 253.00

Human [Leu60] IGF-I

ABU100 100 µg
EUR 346.00

Human [Arg6] IGF-II

GU020 20 µg
EUR 253.00

rec IGF-I (human)

H-5555.0050 50.0µg
EUR 242.00
Description: CAS# [67763-96-6]

rec IGF-I (human)

H-5555.0100 100.0µg
EUR 381.00
Description: CAS# [67763-96-6]

rec IGF-I (human)

H-5555.0500 0.5mg
EUR 1434.00
Description: CAS# [67763-96-6]

IGF-1, human recombinant

P1016-.02 20 µg
EUR 258.00
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue

IGF-1, human recombinant

P1016-.1 100 µg
EUR 763.00
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue

IGF-II, human recombinant

P1017-.01 10 µg
EUR 161.00
Description: Insulin-like Growth Factor-II (IGF-II) is a polypeptide endocrine hormone structurally similar to insulin and belongs to insulin-like growth factor family.

IGF-II, human recombinant

P1017-.05 50 µg
EUR 313.00
Description: Insulin-like Growth Factor-II (IGF-II) is a polypeptide endocrine hormone structurally similar to insulin and belongs to insulin-like growth factor family.

IGF-II, human recombinant

P1017-1 1 mg
EUR 1998.00
Description: Insulin-like Growth Factor-II (IGF-II) is a polypeptide endocrine hormone structurally similar to insulin and belongs to insulin-like growth factor family.

Human [Leu27]IGF-II

TU100 100 µg
EUR 346.00

Human IGF-1 LR3

SP-89927-100 100 ug
EUR 225.00

Human [Leu24] IGF-I

ZU020 20 µg
EUR 253.00

Human [Leu24] IGF-I

ZU100 100 µg
EUR 346.00

IGF-2/ Rat IGF- 2 ELISA Kit

ELA-E0051r 96 Tests
EUR 886.00

Anti-IGF1/Igf I Rabbit Monoclonal Antibody

M00148 100ug/vial
EUR 397.00
Description: Rabbit Monoclonal IGF1/Igf I Antibody. Validated in WB and tested in Human.

Anti-IGF2/Igf Ii Rabbit Monoclonal Antibody

M00335 100ug/vial
EUR 397.00
Description: Rabbit Monoclonal IGF2/Igf Ii Antibody. Validated in IF, WB and tested in Human.

Anti-Phospho-IGF-IR (Y1165/Y1166) antibody

STJ90299 200 µl
EUR 197.00
Description: Rabbit polyclonal to Phospho-IGF-IR (Y1165/Y1166).

Mouse Anti-Human IGF-1R monoclonal antibody, clone JID716

CABT-L2807-100uL500uL 100 uL, 500 uL
EUR 502.00

Recombinant Human IGF-2/ IGF-II Protein, Untagged, E.coli-100ug

QP5264-100ug 100ug
EUR 363.00

Recombinant Human IGF-2/ IGF-II Protein, Untagged, E.coli-10ug

QP5264-10ug 10ug
EUR 136.00

Recombinant Human IGF-2/ IGF-II Protein, Untagged, E.coli-1mg

QP5264-1mg 1mg
EUR 1261.00

Recombinant Human IGF-2/ IGF-II Protein, Untagged, E.coli-500ug

QP5264-500ug 500ug
EUR 762.00

Recombinant Human IGF-2/ IGF-II Protein, Untagged, E.coli-50ug

QP5264-50ug 50ug
EUR 237.00

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-100ug

QP8601-ec-100ug 100ug
EUR 408.00

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-10ug

QP8601-ec-10ug 10ug
EUR 200.00

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-1mg

QP8601-ec-1mg 1mg
EUR 1632.00

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-200ug

QP8601-ec-200ug 200ug
EUR 634.00

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-500ug

QP8601-ec-500ug 500ug
EUR 1060.00

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-50ug

QP8601-ec-50ug 50ug
EUR 263.00

R³ IGF-1, human recombinant

4216-100
EUR 164.00

R³ IGF-1, human recombinant

4216-1G
EUR 40015.00

R³ IGF-1, human recombinant

4216-1MG
EUR 321.00

R³ IGF-1, human recombinant

4216-20MG
EUR 2051.00

R³ IGF-1, human recombinant

4216-50MG
EUR 3470.00

R³ IGF-1, human recombinant

4216-5MG
EUR 843.00

Mono-biotinyl Human IGF-II

AMU010 10 µg
EUR 253.00

Mono-biotinyl Human IGF-II

AMU050 50 µg
EUR 346.00

Di-biotinyl Human IGF-II

ANU010 10 µg
EUR 253.00

Human IGF-I (Receptor Grade)

CU020 20 µg
EUR 253.00

Human IGF-I (Receptor Grade)

CU100 100 µg
EUR 346.00

Human IGF-2 ELISA Kit

EHI0307 96Tests
EUR 521.00

IGF-1 ELISA KIT|Human

EF000135 96 Tests
EUR 689.00

IGF-2 ELISA KIT|Human

EF000742 96 Tests
EUR 689.00

Human IGF-I (Receptor Grade)

CM001 1 mg
EUR 902.00

Human IGF-I (Receptor Grade)

CM005 5 mg
EUR 163.00

Human [Leu24] [Ala31] IGF-I

ADU020 20 µg
EUR 253.00

Human LR3 IGF-I ELISA

BEK-2233-1P 1 Plate Kit
EUR 529.00

Human LR3 IGF-I ELISA

BEK-2233-2P 2 Plate Kit
EUR 900.00

Human [Ala31] [Leu60] IGF-I

ALU020 20 µg
EUR 253.00

Human [Ala31] [Leu60] IGF-I

ALU100 100 µg
EUR 346.00