Parameter identifiability evaluation and visualization in large-scale kinetic fashions of biosystems.

BACKGROUND

Kinetic fashions of biochemical methods normally include odd differential equations which have many unknown parameters. A few of these parameters are sometimes virtually unidentifiable, that’s, their values can’t be uniquely decided from the out there knowledge.

Attainable causes are lack of affect on the measured outputs, interdependence amongst parameters, and poor knowledge high quality. Uncorrelated parameters might be seen as the important thing tuning knobs of a predictive mannequin. Due to this fact, earlier than making an attempt to carry out parameter estimation (mannequin calibration) it is very important characterize the subset(s) of identifiable parameters and their interaction. As soon as that is achieved, it’s nonetheless essential to carry out parameter estimation, which poses further challenges.

METHODS

We current a technique that (i) detects high-order relationships amongst parameters, and (ii) visualizes the outcomes to facilitate additional evaluation. We use a collinearity index to quantify the correlation between parameters in a gaggle in a computationally environment friendly method. Then we apply integer optimization to search out the biggest teams of uncorrelated parameters. We additionally use the collinearity index to establish small teams of extremely correlated parameters. The outcomes recordsdata might be visualized utilizing Cytoscape, exhibiting the identifiable and non-identifiable teams of parameters along with the mannequin construction in the identical graph.

RESULTS

Our contributions alleviate the difficulties that seem at totally different levels of the identifiability evaluation and parameter estimation course of. We present easy methods to mix world optimization and regularization methods for calibrating medium and huge scale organic fashions with average computation occasions.

Then we consider the sensible identifiability of the estimated parameters utilizing the proposed methodology. The identifiability evaluation methods are applied as a MATLAB toolbox known as VisId, which is freely out there as open supply from GitHub ( https://github.com/gabora/visid ).

CONCLUSIONS

Our strategy is geared in the direction of scalability. It permits the sensible identifiability evaluation of dynamic fashions of enormous dimension, and accelerates their calibration. The visualization device permits modellers to detect elements which might be problematic and want refinement or reformulation, and offers experimentalists with info that may be useful within the design of recent experiments.

Validation of the Utilized Biosystems RapidFinder Shiga Toxin-Producing E. coli (STEC) Detection Workflow.

The Utilized Biosystems™ RapidFinder™ STEC Detection Workflow (Thermo Fisher Scientific) is a whole protocol for the speedy qualitative detection of Escherichia coli (E. coli) O157:H7 and the “Huge 6” non-O157 Shiga-like toxin-producing E. coli (STEC) serotypes (outlined as serogroups: O26, O45, O103, O111, O121, and O145).

The RapidFinder STEC Detection Workflow makes use of both the automated preparation of PCR-ready DNA utilizing the Utilized Biosystems PrepSEQ™ Nucleic Acid Extraction Package along side the Utilized Biosystems MagMAX™ Specific 96-well magnetic particle processor or the Utilized Biosystems PrepSEQ Speedy Spin equipment for handbook preparation of PCR-ready DNA.

Two separate assays comprise the RapidFinder STEC Detection Workflow, the Utilized Biosystems RapidFinder STEC Screening Assay and the Utilized Biosystems RapidFinder STEC Affirmation Assay. The RapidFinder STEC Screening Assay contains primers and probes to detect the presence of stx1 (Shiga toxin 1), stx2 (Shiga toxin 2), eae (intimin), and E. coli O157 gene targets. The RapidFinder STEC Affirmation Assay contains primers and probes for the “Huge 6″ non-O157 STEC and E. coli O157:H7. Using these two assays in tandem permits a person to detect precisely the presence of the “Huge 6” STECs and E. coli O157:H7. The efficiency of the RapidFinder STEC Detection Workflow was evaluated in a technique comparability research, in inclusivity and exclusivity research, and in a robustness analysis.

The assays had been in comparison with the U.S. Division of Agriculture (USDA), Meals Security and Inspection Service (FSIS) Microbiology Laboratory Guidebook (MLG) 5.09: Detection, Isolation and Identification of Escherichia coli O157:H7 from Meat Merchandise and Carcass and Environmental Sponges for uncooked floor beef (73% lean) and USDA/FSIS-MLG 5B.05: Detection, Isolation and Identification of Escherichia coli non-O157:H7 from Meat Merchandise and Carcass and Environmental Sponges for uncooked beef trim. No statistically important variations had been noticed between the reference methodology and the person or mixed kits forming the candidate assay utilizing both of the DNA preparation kits (handbook or automated extraction). For the inclusivity and exclusivity analysis, the RapidFinder STEC Detection Workflow, comprising each RapidFinder STEC screening and affirmation kits, accurately recognized all 50 goal organism isolates and accurately excluded all 30 nontarget strains for each of the assays evaluated.

The outcomes of those research reveal the sensitivity and selectivity of the RapidFinder STEC Detection Workflow for the detection of E. coli O157:H7 and the “Huge 6” STEC serotypes in each uncooked floor beef and beef trim. The robustness testing demonstrated that minor variations within the methodology parameters didn’t influence the accuracy of the assay and highlighted the significance of following the right incubation temperatures.

uwmembraneproteins
uwmembraneproteins

Mouse beta Thromboglobulin (CXCL7/bTG) CLIA Kit

20-abx491403
  • EUR 9567.60
  • EUR 5095.20
  • EUR 1177.20
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

NAP-2 Antibody / CXCL7

R31872 100 ug
EUR 356.15
Description: Chemokine (C-X-C motif) ligand 7 (CXCL7), also known as NAP-2 or Pro-Platelet basic protein (PPBP), is a human gene. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Furthermore, the protein is an antimicrobial protein with bactericidal and antifungal activity.

CXCL7/NAP-2

PR27118 2 ug
EUR 229.2

Human NAP2(CXCL7)

90222-A 2 µg
EUR 130
Description: Recombinant NAP-2 is a disulfide-linked monomeric protein consisting of 71 amino acid residues and migrates as an approximately 8 kDa protein under non-reducing conditions and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human NAP-2 (CXCL7) mature chain was expressed in E. coli.

Human NAP2(CXCL7)

90222-B 10 µg
EUR 205
Description: Recombinant NAP-2 is a disulfide-linked monomeric protein consisting of 71 amino acid residues and migrates as an approximately 8 kDa protein under non-reducing conditions and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human NAP-2 (CXCL7) mature chain was expressed in E. coli.

CXCL7 Recombinant Protein

91-045 0.05 mg
EUR 821.4
Description: Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domain containing CXC chemokines, such as IL-8 and the GRO proteins, CXCL7 binds CXCR2, chemoattracts and activates neutrophils. CXCL7, Connective Tissue Activating Protein III (CTAPIII) and beta thrombogulin ( beta TG), are proteolytically processed carboxylterminal fragments of platelet basic protein (PBP) which is found in the alphagranules of human platelets. Although CTAPIII, beta TG, and PBP represent amino-terminal extended variants of NAP2 and possess the same CXC chemokine domains, these proteins do not exhibit CXCL7/NAP2 activity. CXCL7 induces cell migration through the G-protein-linked receptor CXCR-2.

CXCL7 Recombinant Protein

92-388 0.05 mg
EUR 437.1
Description: Human Chemokine (C-X-C motif) Ligand 7 (CXCL7), also known as neutrophil activating peptide 2 (NAP-2), is a member of the CXC chemokines containing an ELR domain (Glu-Leu-Arg tripeptide motif). Similar to other ELR domain containing CXC chemokines, such as IL-8 and the GRO proteins, CXCL7 binds CXCR2, chemoattracts and activates neutrophils. CXCL7, Connective Tissue Activating Protein III (CTAPIII) and beta thrombogulin ( beta TG), are proteolytically processed carboxylterminal fragments of platelet basic protein (PBP) which is found in the alphagranules of human platelets. Although CTAPIII, beta TG, and PBP represent amino-terminal extended variants of NAP2 and possess the same CXC chemokine domains, these proteins do not exhibit CXCL7/NAP2 activity. CXCL7 induces cell migration through the G-protein-linked receptor CXCR-2.

NAP-2 Antibody / CXCL7 / PPBP

RQ4113 100 ug
EUR 356.15
Description: Chemokine (C-X-C motif) ligand 7 (CXCL7), also known as NAP2 or Pro-Platelet basic protein (PPBP), is a human gene. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Furthermore, the protein is an antimicrobial protein with bactericidal and antifungal activity.

NAP-2/CXCL7, Rat

HY-P7269 50ug
EUR 639.6

NAP-2, CXCL7, rat

RC352-18 2ug
EUR 125.26

NAP-2/CXCL7, Human

HY-P7268 50ug
EUR 639.6

NAP-2, CXCL7, human

RC312-18 2ug
EUR 125.26

Human CXCL7 ELISA Kit

LF-EK50893 1×96T
EUR 777.6

CXCL7 ELISA KIT|Human

EF001450 96 Tests
EUR 826.8

Human CXCL7 Antibody (Biotin Conjugate)

32852-05121 150 ug
EUR 442.8

ELISA kit for Mouse ?TG/PBP/CXCL7/NAP2 (Thromboglobulin, Beta)

E-EL-M1269 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Mouse ?TG/PBP/CXCL7/NAP2 (Thromboglobulin, Beta) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human CXCL7

EK5304 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Human CXCL7 in samples from serum, plasma, tissue homogenates and other biological fluids.

Human CXCL7 AssayLite Antibody (RPE Conjugate)

32852-05151 150 ug
EUR 513.6

Human CXCL7 AssayLite Antibody (APC Conjugate)

32852-05161 150 ug
EUR 513.6

Human CXCL7 AssayMax ELISA Kit

EC2270-1 96 Well Plate
EUR 572.4

Human CXCL7 PicoKine ELISA Kit

EK0729 96 wells
EUR 510
Description: For quantitative detection of human CXCL7 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Human CXCL7 AssayLite Antibody (FITC Conjugate)

32852-05141 150 ug
EUR 513.6

Human CXCL7 AssayLite Antibody (PerCP Conjugate)

32852-05171 150 ug
EUR 565.2

Neutrophil Activating Protein-2 (CXCL7) Antibody

20-abx137035
  • EUR 427.20
  • EUR 627.60
  • 0.5 mg
  • 1 mg

Nori® Canine CXCL7 ELISA Kit

GR115398 96-well
EUR 461

Nori Equine CXCL7/NAP2 ELISA Kit

GR106909 96-well
EUR 461

Rat PPBP/CXCL7 PicoKine ELISA Kit

EK0731 96 wells
EUR 510
Description: For Quantitative Detection of rat CXCL7 in cell culture supernates, serum and plasma (heparin, EDTA).

NAP-2/CXCL7 (CHO-expressed), Human

HY-P7267 50ug
EUR 596.4

Recombinant Human CXCL7/NAP-2 Protein

RP00829 10 μg
EUR 265.2

ThymusChemokine‑1/CXCL7 (CHO-expressed), Rat

HY-P7301 10ug
EUR 349.2

Nori® Human CXCL7-NAP2 ELISA Kit

GR106282 96-well
EUR 461

Neutrophil Activating Protein-2 (CXCL7) Protein

20-abx261559
  • EUR 393.60
  • EUR 4101.60
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Neutrophil Activating Protein-2 (CXCL7) Protein

20-abx261561
  • EUR 393.60
  • EUR 4101.60
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Human CXCL7(Platelet basic protein) ELISA Kit

EH0007 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Rabbit Anti Mouse Cxcl1 Polyclonal Antibody

CPBT-65100RM 0.1 mg
EUR 1057.2

Human CXCL7 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

EZ0729 5 plates/kit
EUR 321.6
Description: For the development of sandwich ELISA kit to measure human CXCL7 in cell culture supernates, cell lysates, tissue homogenates, serum and plasma (heparin, EDTA).

Recombinant Rat Neutrophil Activating Protein-2 (CXCL7)

7-02065 2µg Ask for price

Recombinant Rat Neutrophil Activating Protein-2 (CXCL7)

7-02066 10µg Ask for price

Recombinant Rat Neutrophil Activating Protein-2 (CXCL7)

7-02067 1mg Ask for price

Rat Platelet Basic Protein / CXCL7 (PPBP) ELISA Kit

abx255841-96tests 96 tests
EUR 801.6

Pig Platelet Basic Protein / CXCL7 (PPBP) ELISA Kit

abx511493-96tests 96 tests
EUR 1093.2

Recombinant Human Neutrophil Activating Protein-2 (CXCL7)

7-02059 2µg Ask for price

Recombinant Human Neutrophil Activating Protein-2 (CXCL7)

7-02060 10µg Ask for price

Recombinant Human Neutrophil Activating Protein-2 (CXCL7)

7-02061 1mg Ask for price

Human Platelet Basic Protein / CXCL7 (PPBP) ELISA Kit

abx252283-96tests 96 tests
EUR 801.6

Neutrophil Activating Protein-2 (CXCL7), 95 a.a. Protein

20-abx260678
  • EUR 393.60
  • EUR 4101.60
  • EUR 276.00
  • 10 ug
  • 1 mg
  • 2 µg

Mouse Anti-Human CXCL13 monoclonal antibody, clone JID662

CABT-L2832-100uL500uL 100 uL, 500 uL
EUR 602.4

Recombinant (E.Coli) Human Neutrophil Activating Protein-2 (CXCL7)

RP-1008 10 ug
EUR 343.2

Human Thromboglobulin, Beta (bTG/PBP/CXCL7/NAP2) CLIA Kit

abx197774-96tests 96 tests
EUR 990

Recombinant Human Neutrophil Activating Protein-2 (CXCL7), 95 a.a.

7-02062 2µg Ask for price

Recombinant Human Neutrophil Activating Protein-2 (CXCL7), 95 a.a.

7-02063 10µg Ask for price

Recombinant Human Neutrophil Activating Protein-2 (CXCL7), 95 a.a.

7-02064 1mg Ask for price

ELISA kit for Rat ?TG/PBP/CXCL7/NAP2 (Thromboglobulin, Beta)

E-EL-R1087 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Rat ?TG/PBP/CXCL7/NAP2 (Thromboglobulin, Beta) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human ?TG/PBP/CXCL7/NAP2 (Thromboglobulin, Beta)

E-EL-H1007 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human ?TG/PBP/CXCL7/NAP2 (Thromboglobulin, Beta) in samples from Plasma

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, GST, E.coli-1mg

QP8641-ec-1mg 1mg
EUR 1958.4

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, GST, E.coli-10ug

QP8641-ec-10ug 10ug
EUR 240

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, GST, E.coli-50ug

QP8641-ec-50ug 50ug
EUR 315.6

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, GST, E.coli-100ug

QP8641-ec-100ug 100ug
EUR 489.6

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, GST, E.coli-200ug

QP8641-ec-200ug 200ug
EUR 760.8

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, GST, E.coli-500ug

QP8641-ec-500ug 500ug
EUR 1272

Recombinant Rat NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-2ug

QP10285-ec-2ug 2ug
EUR 184.8

Recombinant Human C-X-C Motif Chemokine 7/CXCL7/NAP-2

C056-10ug 10ug
EUR 242.4
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human C-X-C Motif Chemokine 7/CXCL7/NAP-2

C056-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human C-X-C Motif Chemokine 7/CXCL7/NAP-2

C056-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human C-X-C Motif Chemokine 7/CXCL7/NAP-2

C056-50ug 50ug
EUR 595.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Rat NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-10ug

QP10285-ec-10ug 10ug
EUR 348

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-2ug

QP10212-ec-2ug 2ug
EUR 184.8

Recombinant Rat NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-100ug

QP10285-ec-100ug 100ug
EUR 1413.6

Recombinant Rat NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-250ug

QP10285-ec-250ug 250ug
EUR 2480.4

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-10ug

QP10212-ec-10ug 10ug
EUR 348

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-100ug

QP10212-ec-100ug 100ug
EUR 1185.6

Recombinant Human NAP-2/ PPBP/ CXCL7 Protein, Untagged, E.coli-250ug

QP10212-ec-250ug 250ug
EUR 2077.2

Polyclonal (Mouse) Cxcl12 Antibody

APR10977G 0.1ml
EUR 633.6
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human (Mouse) Cxcl12 . This antibody is tested and proven to work in the following applications:

NAP-2 Neutrophil Activating Protein-2 Rat Recombinant Protein (CXCL7)

PROTQ99ME0 Regular: 10ug
EUR 380.4
Description: NAP-2 Rat Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 62 amino acids and having a molecular mass of 6.8kDa.;The NAP 2 is purified by proprietary chromatographic techniques.

NAP-2 Neutrophil Activating Protein-2 Human Recombinant Protein (CXCL7)

PROTP02775 Regular: 10ug
EUR 380.4
Description: Neutrophil Activating Protein-2 Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 70 amino acids and having a molecular mass of 7609 Dalton. ;The NAP-2 is purified by proprietary chromatographic techniques.

CXCL16, Mouse

HY-P7151 10ug
EUR 321.6

Genorise® Mouse CXCL10 Polyclonal Antibody

GR131005 100 µg
EUR 398

Mouse CXCL10 ELISA Kit

55R-1745 1 kit
EUR 781.2
Description: ELISA kit for detection of CXCL10 in the research laboratory

Mouse CXCL16 ELISA Kit

55R-1746 1 kit
EUR 781.2
Description: ELISA kit for detection of CXCL16 in the research laboratory

Mouse CXCL16 ELISA kit

55R-2086 96 tests
EUR 854.4
Description: ELISA Kit for detection of CXCL16 in the research laboratory

Mouse CXCL16 ELISA Kit

EMC0858 96Tests
EUR 625.2

Mouse CXCL16 ELISA kit

LF-EK50573 1×96T
EUR 777.6

Mouse CXCL10 ELISA Kit

STJ150228 1 kit
EUR 494.4
Description: The kit is a sandwich enzyme immunoassay for in vitro quantitative measurement of IP-10/CXCL10 in Mouse serum, plasma and other biological fluids

CXCL3, Mouse

HY-P7153 50ug
EUR 804

Recombinant Mouse CXCL16

7-01804 5µg Ask for price

Recombinant Mouse CXCL16

7-01805 25µg Ask for price

Recombinant Mouse CXCL16

7-01806 1mg Ask for price

CXCL16, murine (mouse)

RC332-27 5ug
EUR 125.26

IP-10/CXCL10, Mouse

HY-P7227 50ug
EUR 639.6

CXCL16 protein (mouse)

30R-AC078 25 ug
EUR 327.6
Description: Purified recombinant Mouse CXCL16 protein

Mouse CXCL13/BLC ELISA Kit

LF-EK50896 1×96T
EUR 777.6

ELISA kit for Mouse CXCL16

EK5311 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CXCL16 in samples from serum, plasma, tissue homogenates and other biological fluids.

Mouse CXCL16 shRNA Plasmid

20-abx975400
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL15 shRNA Plasmid

20-abx972610
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL12 shRNA Plasmid

20-abx972614
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL13 shRNA Plasmid

20-abx974578
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL11 shRNA Plasmid

20-abx974608
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL14 shRNA Plasmid

20-abx974959
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL17 shRNA Plasmid

20-abx982011
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL10 shRNA Plasmid

20-abx970969
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL10/IP10 ELISA Kit

RK00056 96 Tests
EUR 625.2

Mouse CXCL16 ELISA kit (4X96T)

LF-EK50574 4×96T
EUR 2641.2

Mouse CXCL10/IP-10 ELISA kit

LF-EK50521 1×96T
EUR 777.6

Nori® Mouse CXCL16 ELISA Kit

GR117221 96-well
EUR 461

Mouse CXCL12/SDF-1 ELISA Kit

RK00168 96 Tests
EUR 625.2

Mouse CXCL1 ELISA Kit

55R-1741 1 kit
EUR 748.8
Description: ELISA kit for detection of CXCL1 in the research laboratory

BRAK, CXCL14, murine (mouse)

RC332-25 5ug
EUR 125.26

Mouse CXCL17 PicoKine ELISA Kit

EK1768 96 wells
EUR 510
Description: For quantitative detection of mouse CXCL17 in cell culture supernates, serum and plasma (heparin, EDTA, citrate).

Mouse CXCL16 PicoKine ELISA Kit

EK0742 96 wells
EUR 547.2
Description: For quantitative detection of mouse CXCL16 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

NAP-2-95 Neutrophil Activating Protein-2 (CXCL7) Human Recombinant Protein, 95 a.a.

PROTP02775-1 Regular: 10ug
EUR 380.4
Description: NAP 2 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 95 amino acids (35-128) and having a molecular mass of 10.3 kDa.;The NAP 2 is purified by proprietary chromatographic techniques.

SDF-1 alpha/CXCL12, Mouse

HY-P7285 50ug
EUR 639.6

Mouse CXCL14 Detection Assay Kit

6727 1 kit
EUR 580.26
Description: Mouse CXCL14 Detection Assay Kit

Mouse CXCL1 AssayLite Antibody (FITC Conjugate)

70027-05141 150 ug
EUR 513.6

Recombinant Mouse CXCL16 Protein

RP01061 10 μg
EUR 242.4

Mouse CXCL12 Recombinant Protein

R00053 5ug/vial
EUR 310.8
Description: The C-X-C motif chemokine CXCL12 binds to one single chemokine receptor, CXCR4, to mediate cell-type specific physiological processes, including cellular migration, survival, and apoptosis. CXCL12 and its receptor CXCR4 play a role in many different diseases, including cancer, HIV, and rheumatoid arthritis. Mouse CXCL12 Recombinant Protein is purified CXCL12 produced in yeast.

Mouse CXCL10 Recombinant Protein

R00278-5 5ug/vial
EUR 310.8
Description: The ELR-negative CXC chemokine CXCL10 (IP-10) has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis. Mouse CXCL10 Recombinant Protein is purified CXCL10 (IP-10) produced in yeast.

Mouse CXCL1/KC ELISA Kit

RK00038 96 Tests
EUR 625.2

ELISA kit for Mouse CXCL10/IP-10

EK5308 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CXCL10/IP-10 in samples from serum, plasma, tissue homogenates and other biological fluids.

MIP-2/CXCL2, Mouse

HY-P7258 50ug
EUR 817.2

IP-10, CXCL10, murine (mouse)

RC332-21 5ug
EUR 125.26

anti- CXCL11 antibody

FNab02092 100µg
EUR 606.3
Description: Antibody raised against CXCL11

anti- CXCL12 antibody

FNab02093 100µg
EUR 658.5
Description: Antibody raised against CXCL12

anti- CXCL13 antibody

FNab02094 100µg
EUR 606.3
Description: Antibody raised against CXCL13

anti- CXCL14 antibody

FNab02095 100µg
EUR 606.3
Description: Antibody raised against CXCL14

anti- CXCL16 antibody

FNab02096 100µg
EUR 606.3
Description: Antibody raised against CXCL16

anti- CXCL17 antibody

FNab02097 100µg
EUR 606.3
Description: Antibody raised against CXCL17

Mouse CXCL4/PF4 ELISA Kit

LF-EK50892 1×96T
EUR 777.6

ELISA kit for Mouse CXCL1

EK5299 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CXCL1 in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Mouse CXCL9

EK5306 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CXCL9 in samples from serum, plasma, tissue homogenates and other biological fluids.

ELISA kit for Mouse CXCL3

EK5628 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CXCL3 in samples from serum, plasma, tissue homogenates and other biological fluids.

Mouse CXCL4/PF4 ELISA Kit

RK00190 96 Tests
EUR 625.2

CXCL16 protein (Mouse) (His tag)

80R-3350 50 ug
EUR 308.4
Description: Purified recombinant CXCL16 protein (Mouse) (His tag)

CXCL12 protein (Mouse) (His tag)

80R-3356 50 ug
EUR 308.4
Description: Purified recombinant CXCL12 protein (Mouse) (His tag)

CXCL25 protein (Mouse) (His tag)

80R-3357 50 ug
EUR 308.4
Description: Purified recombinant CXCL25 protein (Mouse) (His tag)

CXCL11 protein (Mouse) (His tag)

80R-3466 50 ug
EUR 308.4
Description: Purified recombinant CXCL11 protein (Mouse) (His tag)

Cxcl10 ORF Vector (Mouse) (pORF)

ORF042287 1.0 ug DNA
EUR 114

Cxcl11 ORF Vector (Mouse) (pORF)

ORF042288 1.0 ug DNA
EUR 607.2

Cxcl12 ORF Vector (Mouse) (pORF)

ORF042289 1.0 ug DNA
EUR 607.2

Cxcl12 ORF Vector (Mouse) (pORF)

ORF042290 1.0 ug DNA
EUR 607.2

Cxcl12 ORF Vector (Mouse) (pORF)

ORF042291 1.0 ug DNA
EUR 607.2

Cxcl13 ORF Vector (Mouse) (pORF)

ORF042292 1.0 ug DNA
EUR 607.2

Cxcl14 ORF Vector (Mouse) (pORF)

ORF042293 1.0 ug DNA
EUR 607.2

Cxcl15 ORF Vector (Mouse) (pORF)

ORF042294 1.0 ug DNA
EUR 607.2

Cxcl16 ORF Vector (Mouse) (pORF)

ORF042295 1.0 ug DNA
EUR 607.2

Cxcl17 ORF Vector (Mouse) (pORF)

ORF042296 1.0 ug DNA
EUR 607.2

Mouse CXCL13/BLC PicoKine ELISA Kit

EK0740 96 wells
EUR 510
Description: For quantitative detection of mouse CXCL13 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Mouse CXCL2 shRNA Plasmid

20-abx972611
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL5 shRNA Plasmid

20-abx972612
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL3 shRNA Plasmid

20-abx983594
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL1 shRNA Plasmid

20-abx970673
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL9 shRNA Plasmid

20-abx971513
  • EUR 961.20
  • EUR 1345.20
  • 150 µg
  • 300 µg

Mouse CXCL10/IP-10 ELISA kit (4X96T)

LF-EK50522 4×96T
EUR 2641.2

Mouse CXCL1/GROα ELISA kit

LF-EK50473 1×96T
EUR 777.6

Nori® Mouse CXCL10/IP-10 ELISA Kit

GR117051 96-well
EUR 461

IP-10/CXCL10 (Mouse) ELISA Kit

E4827-100 96 assays
EUR 661.2

Mouse Cx3CL1 ELISA Kit

EMC0239 96Tests
EUR 625.2

Mouse CXCL3 EZ-Set™ ELISA Kit (DIY Antibody Pairs)

EZ1364 5 plates/kit
EUR 388.8
Description: For the development of sandwich ELISA kit to measure mouse CXCL3 in cell culture supernates, serum and plasma(heparin, EDTA).

Mouse C-X-C motif chemokine 14 (Cxcl14)

1-CSB-RP093194m
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse C-X-C motif chemokine 14(Cxcl14) expressed in E.coli

Mouse C-X-C motif chemokine 16 (Cxcl16)

1-CSB-RP093374m
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse C-X-C motif chemokine 16(Cxcl16),partial expressed in E.coli

Mouse C-X-C motif chemokine 10 (Cxcl10)

1-CSB-EP006240MO
  • EUR 606.00
  • EUR 318.00
  • EUR 2192.40
  • EUR 919.20
  • EUR 1461.60
  • EUR 402.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Mouse C-X-C motif chemokine 10(Cxcl10) expressed in E.coli

Nori® Mouse CXCL6 ELISA Kit

GR117220 96-well
EUR 461

Nori® Mouse CXCL5 ELISA Kit

GR117396 96-well
EUR 461

ELISA kit for Mouse CXCL4/PF4

EK5303 96 tests
EUR 663.6
Description: Enzyme-linked immunosorbent assay kit for quantification of Mouse CXCL4/PF4 in samples from serum, plasma, tissue homogenates and other biological fluids.

Mouse CXCL10/IP-10 PicoKine ELISA Kit

EK0736 96 wells
EUR 547.2
Description: For quantitative detection of mouse CXCL10 in cell culture supernates, serum and plasma( heparin).

SDF-1 beta, CXCL12, murine (mouse)

RC332-23B 2ug
EUR 125.26

GRO-alpha/CXCL1, Mouse

HY-P7188 50ug
EUR 639.6

Recombinant Mouse IP-10 (CXCL10)

7-01930 5µg Ask for price

Recombinant Mouse IP-10 (CXCL10)

7-01931 25µg Ask for price

Validation of the Utilized Biosystems 7500 Quick Instrument for Detection of Listeria monocytogenes with the SureTect Listeria monocytogenes PCR Assay.

In 2013, the Thermo Scientific™ SureTect™ Listeria monocytogenes Actual-Time PCR Assay was licensed by the AOAC Analysis Institute (RI) Efficiency Examined Strategies(SM) program as a speedy methodology for the detection of L. monocytogenes from a variety of meals matrixes and floor samples.

This report particulars the tactic modification research undertaken to increase the evaluation of this PCR assay to the Utilized Biosystems™ 7500 Quick PCR Instrument and Utilized Biosystems RapidFinder™ Specific 2.zero software permitting the usage of the SureTect assay on a 96 effectively format PCR cycler along with the present workflow, which makes use of the 24 effectively Thermo Scientific PikoReal™ PCR Instrument and Thermo Scientific SureTect software program.

As a result of this research was deemed by AOAC-RI to be a degree 2 methodology modification research, a consultant vary of meals matrixes overlaying uncooked floor turkey, 2% fats pasteurized milk, and bagged lettuce in addition to chrome steel floor samples had been analyzed with the Utilized Biosystems 7500 Quick PCR Instrument and RapidFinder Specific 2.zero software program.

All testing was carried out compared to the reference methodology detailed in Worldwide Group for Standardization (ISO) 6579:2002. No important distinction by likelihood of detection statistical evaluation was discovered between the SureTect Listeria monocytogenes PCR Assay or the ISO reference methodology strategies for any of the matrixes analyzed throughout the research.

Validation of the Utilized Biosystems 7500 Quick Instrument for the Detection of Salmonellae with SureTect Salmonella Species PCR Package.

The Thermo Scientific SureTect™ Salmonella species real-time PCR assay is a speedy various methodology designed for the detection of salmonellae in a variety of meals, animal feeds, and production-environment samples. The assay has beforehand been validated in accordance with the AOAC Analysis Institute Efficiency Examined Strategies(SM) program utilizing Thermo Scientific PikoReal PCR cycler and Thermo Scientific SureTect Software program Efficiency Examined Methodology 051303).

This report particulars the method-modification research carried out to validate an up to date assay format, using a diminished goal probe focus and an extension of the PCR cycler platform to allow the usage of the equipment with a Utilized Biosystems 7500 Quick PCR cycler and Utilized Biosystems RapidFinder™ Specific 2.zero software program.

Throughout this validation research, a matrix research was carried out on a subset of the tactic’s claimed matrixes, evaluating the efficiency of the modified SureTect Salmonella species equipment (a diminished goal probe focus with a 7500 Quick platform) to the reference methodology detailed in ISO 6579:2002.

No important distinction by likelihood of detection statistical evaluation was discovered between SureTect or Worldwide Group for Standardization strategies for any of the matrixes analyzed throughout the research. Inclusivity and exclusivity research utilizing the modified methodology demonstrated correct outcomes for the 117 Salmonella and 36 non-Salmonella strains examined. A number of manufacturing plenty of the newly formatted equipment had been evaluated and located to be in step with the present assay. Robustness research confirmed that the change to the equipment had no influence on the assay’s efficiency when alterations had been made to methodology parameters having the best potential influence on assay efficiency.

IGF BP7 antibody

70R-IR024 50 ug
EUR 327.6
Description: Affinity purified Rabbit polyclonal IGF BP7 antibody

IGF-BP3, Human

HY-P7020 10ug
EUR 280.8

IGF-BP5, Human

HY-P7021 50ug
EUR 721.2

IGF-BP3, human

RC216-12B3 5ug
EUR 125.26

IGF BP2 protein

30R-AI105 20 ug
EUR 327.6
Description: Purified recombinant Human IGF BP2 protein

IGF BP6 protein

30R-AI106 25 ug
EUR 327.6
Description: Purified recombinant Human IGF BP6 protein

IGF BP7 protein

30R-AI120 25 ug
EUR 327.6
Description: Purified recombinant Human IGF BP7 protein

IGF BP1 protein

30R-AI121 25 ug
EUR 327.6
Description: Purified recombinant Human IGF BP1 protein

IGF BP3 protein

30R-AI122 25 ug
EUR 327.6
Description: Purified recombinant Human IGF BP3 protein

IGF BP5 protein

30R-AI124 25 ug
EUR 327.6
Description: Purified recombinant Human IGF BP5 protein

IGF-1, Human

HY-P7018 10ug
EUR 129.6

IGF-2, Human

HY-P7019 100ug
EUR 432

IGF-1, human

RC216-12 1mg
EUR 451.5

Antibody for Human IGF-1

SPC-699D-ALP 0.1mg
EUR 472.8
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Alkaline Phosphatase.

Antibody for Human IGF-1

SPC-699D-DY350 0.1mg
EUR 496.8
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Dylight 350.

Antibody for Human IGF-1

SPC-699D-DY405 0.1mg
EUR 483.6
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Dylight 405.

Antibody for Human IGF-1

SPC-699D-DY488 0.1mg
EUR 471.6
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Dylight 488.

Antibody for Human IGF-1

SPC-699D 0.1mg
EUR 424.8
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is unconjugated.

Antibody for Human IGF-1

SPC-699D-A390 0.1mg
EUR 481.2
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 390.

Antibody for Human IGF-1

SPC-699D-A488 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 488.

Antibody for Human IGF-1

SPC-699D-A565 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 565.

Antibody for Human IGF-1

SPC-699D-A594 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 594.

Antibody for Human IGF-1

SPC-699D-A633 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 633.

Antibody for Human IGF-1

SPC-699D-A655 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 655.

Antibody for Human IGF-1

SPC-699D-A680 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 680.

Antibody for Human IGF-1

SPC-699D-A700 0.1mg
EUR 480
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to ATTO 700.

Antibody for Human IGF-1

SPC-699D-APC 0.1mg
EUR 478.8
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to APC .

Antibody for Human IGF-1

SPC-699D-APCCY7 0.1mg
EUR 565.2
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to APC/Cy7.

Antibody for Human IGF-1

SPC-699D-BI 0.1mg
EUR 475.2
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Biotin.

Antibody for Human IGF-1

SPC-699D-DY594 0.1mg
EUR 474
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Dylight 594.

Antibody for Human IGF-1

SPC-699D-DY633 0.1mg
EUR 468
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Dylight 633.

Antibody for Human IGF-1

SPC-699D-FITC 0.1mg
EUR 470.4
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to FITC.

Antibody for Human IGF-1

SPC-699D-HRP 0.1mg
EUR 465.6
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to HRP.

Antibody for Human IGF-1

SPC-699D-P594 0.1mg
EUR 488.4
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to PE/ATTO 594.

Antibody for Human IGF-1

SPC-699D-PCP 0.1mg
EUR 478.8
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to PerCP.

Antibody for Human IGF-1

SPC-699D-RPE 0.1mg
EUR 476.4
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to RPE .

Antibody for Human IGF-1

SPC-699D-STR 0.1mg
EUR 477.6
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is conjugated to Streptavidin.

Antibody for Human IGF-1

SPC-699S 0.012mg
EUR 78
Description: A polyclonal antibody for IGF-1 from Human | Mouse. The antibody is produced in rabbit after immunization with human synthetic peptide from the mid-protein of Human IGF-1. The Antibody is tested and validated for WB, ICC/IF, IHC assays with the following recommended dilutions: WB (1:1000); ICC/IF (1:100); IHC (1:50). This IGF-1 antibody is unconjugated.

Human Salivary IGF(salivary IGF) ELISA Kit

QY-E05383 96T
EUR 433.2

Human IGF-1 LR3

SP-89927-100 100 ug
EUR 270

Anti-Rat IGF-1 Antibody

5121-100 each
EUR 379.2

Anti-Rat IGF-1 Antibody

5121-30T each
EUR 175.2

IGF-BP2, human recombinant

7165-10 each
EUR 301.2

IGF-BP2, human recombinant

7165-50 each
EUR 1123.2

IGF-BP7, human recombinant

7167-10 each
EUR 248.4

IGF-BP7, human recombinant

7167-50 each
EUR 810

IGF-BP6, human recombinant

7350-20 each
EUR 444

IGF-BP1, human recombinant

4717-100 each
EUR 744

IGF-BP1, human recombinant

4717-1000 each
EUR 3778.8

IGF-BP1, human recombinant

4717-25 each
EUR 307.2

IGF-BP3, human recombinant

4720-100 each
EUR 744

IGF-BP3, human recombinant

4720-1000 each
EUR 3778.8

IGF-BP3, human recombinant

4720-25 each
EUR 307.2

IGF-BP5, human recombinant

4723-100 each
EUR 744

IGF-BP5, human recombinant

4723-1000 each
EUR 3778.8

IGF-BP5, human recombinant

4723-25 each
EUR 307.2

Human IGF-I monoclonal antibody

MAM1 500 µg
EUR 358.8

IGF-1, human recombinant

P1016-.02 20 µg
EUR 309.6
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue

IGF-1, human recombinant

P1016-.1 100 µg
EUR 915.6
Description: Insulin-like growth factor I (IGF-1) is a polypeptide endocrine hormone structurally similar to insulin and is mainly produced in the liver when stimulated by growth hormone. IGF-1 is a growth factor that stimulates the proliferation of various cell types including muscle, bone, and cartilage tissue

rec IGF-I (human)

H-5555.0050 50.0µg
EUR 290.4
Description: CAS# [67763-96-6]

rec IGF-I (human)

H-5555.0100 100.0µg
EUR 457.2
Description: CAS# [67763-96-6]

rec IGF-I (human)

H-5555.0500 0.5mg
EUR 1720.8
Description: CAS# [67763-96-6]

Human IGF-I Protein

abx060791-100ug 100 ug
EUR 560.4

Biotinyl Human IGF-I

AQU010 10 µg
EUR 303.6

Biotinyl Human IGF-I

AQU050 50 µg
EUR 415.2

Biotinyl Human IGF-I

AQU100 100 µg
EUR 637.2

Biotinyl Human IGF-I

AQU500 500 µg
EUR 1305.6

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-1mg

QP8601-ec-1mg 1mg
EUR 1958.4

Human [Ala31] IGF-I

AIU020 20 µg
EUR 303.6

Human [Ala31] IGF-I

AIU100 100 µg
EUR 415.2

Human [Leu60] IGF-I

ABU020 20 µg
EUR 303.6

Human [Leu60] IGF-I

ABU100 100 µg
EUR 415.2

Human [Arg6] IGF-II

GU020 20 µg
EUR 303.6

Human [Leu24] IGF-I

ZU020 20 µg
EUR 303.6

Human [Leu24] IGF-I

ZU100 100 µg
EUR 415.2

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-10ug

QP8601-ec-10ug 10ug
EUR 240

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-50ug

QP8601-ec-50ug 50ug
EUR 315.6

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-100ug

QP8601-ec-100ug 100ug
EUR 489.6

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-200ug

QP8601-ec-200ug 200ug
EUR 760.8

Recombinant Human IGF-2/ IGF-II Protein, GST, E.coli-500ug

QP8601-ec-500ug 500ug
EUR 1272

Human [Leu27]IGF-II

TU100 100 µg
EUR 415.2

Human IGF-2 ELISA Kit

EHI0307 96Tests
EUR 625.2

Human IGF-1 ELISA Kit

RK00160 96 Tests
EUR 625.2

Recombinant Human IGF-2/ IGF-II Protein, Untagged, E.coli-1mg

QP5264-1mg 1mg
EUR 1513.2

Recombinant Human IGF-2/ IGF-II Protein, Untagged, E.coli-10ug

QP5264-10ug 10ug
EUR 163.2

Recombinant Human IGF-2/ IGF-II Protein, Untagged, E.coli-50ug

QP5264-50ug 50ug
EUR 284.4

Recombinant Human IGF-2/ IGF-II Protein, Untagged, E.coli-100ug

QP5264-100ug 100ug
EUR 435.6

Recombinant Human IGF-2/ IGF-II Protein, Untagged, E.coli-500ug

QP5264-500ug 500ug
EUR 914.4

Recombinant Human IGF-BP1 Protein

PROTP08833-1 25ug
EUR 380.4
Description: IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP1 is a 25.4 kDa cysteine-rich secreted protein expressed in liver, deciduas, and kidneys and is the most abundant IGF-BP in amniotic fluid. Levels of IGF-BP1 in serum are lowest after food. IGF-BP1 binds to both IGF-I and IGF-II with equal affinity. Phosphorylated IGF-BP1 hinders IGF actions, where as nonphosphorylated IGF-BP1 is stimulatory. Recombinant human IGF-BP1 is a 25.4 kDa protein consisting of 235 amino acid residues (Isoform A).

Recombinant Human IGF-BP3 Protein

PROTP17936-2 25ug
EUR 380.4
Description: IGF-BP3 is a 30 kDa cysteine-rich secreted protein. It is the major IGF binding protein present in the plasma of human and animals and it is also found in α-granules of platelets. In addition to its ability to modulate the activity of IGF-I and IGF-II, IGF-BP3 exerts inhibitory effects on follicle stimulating hormone (FSH) activity. Decreased plasma levels of IGF-BP3 often results in dwarfism, whereas elevated levels of IGF-BP3 may lead to acromegaly. The expression of IGF-BP3 in fibroblasts is stimulated by mitogenic growth factors such as Bombesin, Vasopressin, PDGF, and EGF. Recombinant human IGF-BP3 is a 28.8 kDa protein consisting of 264 amino acid residues.

Recombinant Human IGF-BP2 Protein

PROTP18065 20ug
EUR 380.4
Description: IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP2 is a cysteine-rich secreted protein produced by bone cells, and is most abundant in the brain. IGF-BP2 has been shown to inhibit IGF-II action in human breast and ovarian carcinoma cells. Recombinant human IGF-BP2 is a 31.5 kDa protein consisting of 289 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain.

*Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

Recombinant Human IGF-BP6 Protein

PROTP24592-2 20ug
EUR 380.4
Description: IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. IGF-BP6 is produced by bone cells and is the major IGF-BP present in cerebrospinal fluid, and specifically inhibits IGF-II actions. IGF-BP6 has been shown to inhibit IGF-II-dependent cancers such as neuroblastoma, colon cancer and rhabdomyosarcoma. Recombinant human IGF-BP6 has a calculated mass of 22.6 kDa and consists of 213 amino acid residues including the IGF-BP domain and thyroglobulin type-I domain. IGF-BP6 migrates at an apparent molecular weight of approximately 23.0-30.0 kDa by SDS-PAGE analysis under non-reducing conditions.

*Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

Recombinant Human IGF-BP5 Protein

PROTP24593-1 25ug
EUR 380.4
Description: IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP5 is a 28.6 kDa cysteine-rich secreted protein produced by vascular smooth muscle cells. It is the major IGF-binding protein present in bone tissue and helps potentiate the action of IGF-I on smooth muscle cells, fibroblasts or osteoblasts. Data shows that IGFBP-5 acts as a growth inhibitor and pro-apoptotic agent in breast cancer cells. IGFBP-5 overexpressing mice show an increase in neonatal mortality, reduced female fertility, whole-body growth inhibition and retarded muscle development. Recombinant human IGF-BP5 is a 28.6 kDa protein consisting of 253 amino acid residues.

Recombinant Human IGF-BP7 Protein

PROTQ16270-2 25ug
EUR 380.4
Description: IGF-BPs controls the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF induced differentiation of skeletal myoblasts, without affecting IGF induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF independent mechanism, which causes a delay in the G1 phase of the cell cycle, and increased apoptosis. Recombinant human IGF-BP7 is a 26.4 kDa protein consisting of 256 amino acid residues.

IGF-1, DES1-3, human

RC216-12B 100ug
EUR 203.56

IGF-1 (human) ELISA Kit

K4775-100 100 assays
EUR 970.8
Description: Sensitive, Colorimetric Assay

IGF-1 ELISA KIT|Human

EF000135 96 Tests
EUR 826.8

IGF-2 ELISA KIT|Human

EF000742 96 Tests
EUR 826.8

IGF-I, human recombinant

4119-100 each
EUR 210

IGF-I, human recombinant

4119-1000 each
EUR 411.6

IGF-I, human recombinant

4119-10MG each
EUR 1834.8

IGF-I, human recombinant

4119-1G each
EUR 49388.4

IGF-I, human recombinant

4119-20MG each
EUR 2793.6

IGF-I, human recombinant

4119-5000 each
EUR 1149.6

IGF-I, human recombinant

4119-50MG each
EUR 5064

Polyclonal Anti-Rat IGF-1 Antibody

APR00269G 0.1mg
EUR 580.8
Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human Anti-Rat IGF-1 . This antibody is tested and proven to work in the following applications:

IGF-II, human recombinant

4122-10 each
EUR 164.4

IGF-II, human recombinant

4122-1000 each
EUR 1886.4

IGF-II, human recombinant

4122-50 each
EUR 307.2

IGF-II, human recombinant

P1017-.01 10 µg
EUR 193.2
Description: Insulin-like Growth Factor-II (IGF-II) is a polypeptide endocrine hormone structurally similar to insulin and belongs to insulin-like growth factor family.

IGF-II, human recombinant

P1017-.05 50 µg
EUR 375.6
Description: Insulin-like Growth Factor-II (IGF-II) is a polypeptide endocrine hormone structurally similar to insulin and belongs to insulin-like growth factor family.

IGF-II, human recombinant

P1017-1 1 mg
EUR 2397.6
Description: Insulin-like Growth Factor-II (IGF-II) is a polypeptide endocrine hormone structurally similar to insulin and belongs to insulin-like growth factor family.

IGF-1, N15 labeled, human

RC216-12N 5ug
EUR 125.26

R³ IGF-1, human recombinant

4216-100 each
EUR 196.8

R³ IGF-1, human recombinant

4216-1G each
EUR 48018

R³ IGF-1, human recombinant

4216-1MG each
EUR 385.2

R³ IGF-1, human recombinant

4216-20MG each
EUR 2461.2

R³ IGF-1, human recombinant

4216-50MG each
EUR 4164

R³ IGF-1, human recombinant

4216-5MG each
EUR 1011.6

Human IGF-I Polyclonal Antibody (Rabbit)

PAA2 400 µg
EUR 358.8

Human IGF-II Polyclonal Antibody (Rabbit)

PAC1 400 µg
EUR 358.8

Human LR3 IGF-I monoclonal antibody

MAN100 100 µg
EUR 358.8