Biosystem for Modulation of Interactions between Antigen-Presenting Cells and T Cells

Biosystems Design by Machine Studying

Biosystems corresponding to enzymes, pathways, and complete cells have been more and more explored for biotechnological functions. Nevertheless, the intricate connectivity and ensuing complexity of biosystems poses a significant hurdle in designing biosystems with fascinating options. As -omics and different excessive throughput applied sciences have been quickly developed, the promise of making use of machine studying (ML) strategies in biosystems design has began to change into a actuality.

  • ML fashions allow the identification of patterns inside sophisticated organic information throughout a number of scales of study and might increase biosystems design functions by predicting new candidates for optimized efficiency.
  • ML is getting used at each stage of biosystems design to assist discover nonobvious engineering options with fewer design iterations. On this overview, we first describe generally used fashions and modeling paradigms inside ML.
  • We then focus on some functions of those fashions which have already proven success in biotechnological functions.
  • Furthermore, we focus on profitable functions in any respect scales of biosystems design, together with nucleic acids, genetic circuits, proteins, pathways, genomes, and bioprocesses. Lastly, we focus on some limitations of those strategies and potential options in addition to prospects of the mixture of ML and biosystems design.
uwmembraneprotein
uwmembraneprotein

Human Dkk-1 ELISA Kit

E28L0566 96T
EUR 666.67

Human Dkk-1 ELISA KIT

E42EH-269 96T/48T Ask for price

Human DKK-1 ELISA kit

LF-EK50797 1×96T
EUR 777.6

Human Dkk-1 ELISA Kit

GWB-SKR221 96 Tests Ask for price

Human CellExp? DKK-1, Human Recombinant

7132-10 each
EUR 333.6

Human CellExp? DKK-1, Human Recombinant

7132-50 each
EUR 1358.4

DKK-1 (HEK293-expressed), Human

HY-P7155A 50ug
EUR 1011.6

human Dkk-1 Recombinant Protein

100-407 10 µg
EUR 196.35
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues.

human Dkk-1 Recombinant Protein

100-407S 2 µg
EUR 92.4
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues.

Human Dkk-1 Recombinant Protein

200-013 20 µg
EUR 136.5
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 fused to a C terminal His-tag derived from E. coli is a 26 kDa protein containing 235 amino-acid residues.

Human Dkk-1 Recombinant Protein

200-013S 5 µg
EUR 92.4
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 fused to a C terminal His-tag derived from E. coli is a 26 kDa protein containing 235 amino-acid residues.

Recombinant Human DKK-1 Protein

PROTO94907-3 10ug
EUR 380.4
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues.

Dkk-1

GT30000 50 ug
EUR 631.2

Human DKK Antibody

E63C02401 100ug/100ul
EUR 225
Description: Available in various conjugation types.

Human DKK-1 PicoKine ELISA Kit

EK0867 96 wells
EUR 510
Description: For quantitative detection of human DKK1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Active Recombinant Human Dkk-1 Protein

RP01343 100μg
EUR 162.5

Human DKK-1 Recombinant Protein Lyophilized

IHUDKK1RLY2UG each
EUR 341
Description: Human DKK-1 Recombinant Protein Lyophilized

Human DKK-1 ELISA kit (4×96T)

LF-EK50798 4×96T
EUR 2641.2

Nori® Human DKK-1 ELISA Kit

GR106268 96-well
EUR 461

DKK-1 Antibody

F51803-0.4ML 0.4 ml
EUR 322.15
Description: DKK-1 is a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK-1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.

OKRC00363-96W - Dkk-1 ELISA Kit (Human)

OKRC00363-96W 96Wells
EUR 525

OKAG00221-96W - Dkk-1 ELISA Kit (Human)

OKAG00221-96W 1plate:12x8-WellMicrostrips
EUR 475

Human DKK Antibody-HRP

E63C02402 100ug/100ul
EUR 275
Description: Available in various conjugation types.

DKK-3 ELISA KIT|Human

EF000091 96 Tests
EUR 826.8

Human DKK Antibody-BIOTIN

E63C02403 100ug/100ul
EUR 275
Description: Available in various conjugation types.

Recombinant Human DKK1/Dkk-1 Protein (His Tag)

PKSH033697-10ug 10ug
EUR 178
Description: Human

Recombinant Human DKK1/Dkk-1 Protein (His Tag)

PKSH033697-50ug 50ug
EUR 523
Description: Human

human Dkk-3 Recombinant Protein

100-408 10 µg
EUR 196.35
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-l1 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains.  Playing an important regulatory role in vertebrate development through localized inhibition of Wnt regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-3 has been shown to potentiate, rather than inhibit, Wnt signaling through interactions with the high-affinity, transmembrane coreceptors Kremen-1 (Krm1) and Kremen-2 (Krm2). Recombinant human DKK-3 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 36.3 kDa and contains 329 amino acid residues. Due to glycosylation, human DKK-3 migrates at an apparent molecular weight of approximately 39-49 kDa by SDS-PAGE analysis under non-reducing conditions.

human Dkk-3 Recombinant Protein

100-408S 2 µg
EUR 92.4
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-l1 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains.  Playing an important regulatory role in vertebrate development through localized inhibition of Wnt regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-3 has been shown to potentiate, rather than inhibit, Wnt signaling through interactions with the high-affinity, transmembrane coreceptors Kremen-1 (Krm1) and Kremen-2 (Krm2). Recombinant human DKK-3 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 36.3 kDa and contains 329 amino acid residues. Due to glycosylation, human DKK-3 migrates at an apparent molecular weight of approximately 39-49 kDa by SDS-PAGE analysis under non-reducing conditions.

human Dkk-2 Recombinant Protein

100-436 10 µg
EUR 196.35
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-11 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-2 has been shown to both inhibit and enhance canonical Wnt signaling; enhancing Wnt signaling through direct high-affinity binding of DKK-2 to LRP6 during LRP6 overexpression, while inhibiting Wnt signaling and promoting LRP6 internalization through the formation of a ternary complex between DKK-2, LRP6, and Kremen-2. Recombinant Human DKK-2 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 25.8 kDa and contains 234 amino acid residues. Due to glycosylation, human DKK-2 migrates at an apparent molecular weight of approximately 31-36 kDa by SDS-PAGE analysis under non-reducing conditions.

human Dkk-2 Recombinant Protein

100-436S 2 µg
EUR 92.4
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-11 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-2 has been shown to both inhibit and enhance canonical Wnt signaling; enhancing Wnt signaling through direct high-affinity binding of DKK-2 to LRP6 during LRP6 overexpression, while inhibiting Wnt signaling and promoting LRP6 internalization through the formation of a ternary complex between DKK-2, LRP6, and Kremen-2. Recombinant Human DKK-2 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 25.8 kDa and contains 234 amino acid residues. Due to glycosylation, human DKK-2 migrates at an apparent molecular weight of approximately 31-36 kDa by SDS-PAGE analysis under non-reducing conditions.

Human Dkk-2 Recombinant Protein

200-014 20 µg
EUR 136.5
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-11 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-2 has been shown to both inhibit and enhance canonical Wnt signaling; enhancing Wnt signaling through direct high-affinity binding of DKK-2 to LRP6 during LRP6 overexpression, while inhibiting Wnt signaling and promoting LRP6 internalization through the formation of a ternary complex between DKK-2, LRP6, and Kremen-2. Recombinant Human DKK-2 fused to a C terminal His-tag derived from E. coli has a molecular weight of 26.0 kDa and contains 234 amino acid residues.

Human Dkk-2 Recombinant Protein

200-014S 5 µg
EUR 92.4
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-11 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-2 has been shown to both inhibit and enhance canonical Wnt signaling; enhancing Wnt signaling through direct high-affinity binding of DKK-2 to LRP6 during LRP6 overexpression, while inhibiting Wnt signaling and promoting LRP6 internalization through the formation of a ternary complex between DKK-2, LRP6, and Kremen-2. Recombinant Human DKK-2 fused to a C terminal His-tag derived from E. coli has a molecular weight of 26.0 kDa and contains 234 amino acid residues.

Recombinant Human Dkk-3 Protein

RP00209 10 μg
EUR 97.5

Recombinant Human Dkk-3 Protein

RP00355 10 μg
EUR 196.8

Anti-Human Dkk-1 Antibody

102-PA33 200 µg
EUR 204.75
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 fused to a C terminal His-tag derived from E. coli is a 26 kDa protein containing 235 amino-acid residues.

Anti-Human Dkk-1 Antibody

102-PA33S 100 µg
EUR 126
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 fused to a C terminal His-tag derived from E. coli is a 26 kDa protein containing 235 amino-acid residues.

Anti-Human Dkk-1 Antibody

101-M380 100 µg
EUR 399
Description: Dkk1 is a Dickkopf-related protein that inhibits Wnt signaling by binding the Wnt coreceptor LRP5/6. It also binds Kremen1 and Kremen2. Dkk1 is important in embryonic development.

Anti-Human Dkk-1 Antibody

101-M426 100 µg
EUR 399
Description: Dkk1 is a Dickkopf-related protein that inhibits Wnt signaling by binding the Wnt coreceptor LRP5/6. It also binds Kremen1 and Kremen2. Dkk1 is important in embryonic development.

Human Dkk-1 Protein, Fc Tag (MALS verified)

DK1-H5258 1mg
EUR 310.3
Description: Human Dkk-1, Fc Tag (DK1-H5258) is expressed from human 293 cells (HEK293). It contains AA Thr 32 - His 266 (Accession # NP_036374.1).

Dkk-1 ELISA Kit (Human) : 96 Wells (OKAG00221)

OKAG00221 96 Wells
EUR 715.2
Description: Description of target: This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma.;Species reactivity: Human;Application: ELISA;Assay info: Quantitative Colorimentric Sandwich ELISA;Sensitivity: 63 pg/mL

Human Dkk-1 Protein, His Tag, premium grade

DK1-H5221 1mg
EUR 139.1
Description: Human Dkk-1 Protein, His Tag, premium grade (DK1-H5221) is expressed from human 293 cells (HEK293). It contains AA Thr 32 - His 266 (Accession # NP_036374.1).

Biotinylated Human Dkk-1 Protein, Fc,Avitag™

DK1-H82F5 25ug
EUR 1487.3
Description: Biotinylated Human Dkk-1, Fc,Avitag (DK1-H82F5) is expressed from human 293 cells (HEK293). It contains AA Thr 32 - His 266 (Accession # O94907-1).

Human DKK-1(Dickkopf-related protein 1) ELISA Kit

EH0113 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 18.75pg/ml

Human DKK-1(Dickkopf-related protein 1) ELISA Kit

EKF57029-48T 48T
EUR 396.9

Human DKK-1(Dickkopf-related protein 1) ELISA Kit

EKF57029-5x96T 5x96T
EUR 2693.25

Human DKK-1(Dickkopf-related protein 1) ELISA Kit

EKF57029-96T 96T
EUR 567

Rabbit Anti Human DKK PcAb

E61C02403 100ug
EUR 225
Description: Available in various conjugation types.

Rabbit Anti Human DKK PcAb

E61C02403a 1mg
EUR 1125
Description: Available in various conjugation types.

Dkk-1 Rabbit pAb

E2251891 100ul
EUR 225
Description: Available in various conjugation types.

Recombinant Human DKK-1/DKK1 Protein, 8* His Tag

E40KMH986 20ug
EUR 495

Human DKK-2 Protein, His Tag

DK2-H5323 1mg
EUR 224.7
Description: Human DKK-2 Protein, His Tag (DK2-H5323) is expressed from CHO cells. It contains AA Lys 34 - Ile 259 (Accession # Q9UBU2).

Recombinant Human DKK1/Dkk-1 Protein (His Tag)(Active)

PKSH031807-100ug 100ug
EUR 636
Description: Human

Recombinant Human DKK1/Dkk-1 Protein (His Tag)(Active)

PKSH031807-20ug 20ug
EUR 303
Description: Human

Human DKK-4 PicoKine ELISA Kit

EK0868 96 wells
EUR 546
Description: For Quantitative Detection of human DKK-4 in cell culture supernates, serum and plasma(heparin, EDTA).

Human DKK-3 PicoKine ELISA Kit

EK1323 96 wells
EUR 510
Description: For quantitative detection of human DKK-3 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Dkk-1 Polyclonal Antibody

41928-100ul 100ul
EUR 302.4

Dkk-1 Polyclonal Antibody

41928-50ul 50ul
EUR 224.4

DKK-1 Recombinant Protein

40-225-0002mg 0.002 mg
EUR 311.1
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues.

DKK-1 Recombinant Protein

40-225-001mg 0.01 mg
EUR 437.1
Description: DKK-1 is a member of the DKK protein family which also includes DKK-2, DKK-3 and DKK-4. DKK-1 was originally identified as a Xenopus head forming molecule that behaves as an antagonist for Wnt signaling. Subsequent studies have shown that DKK-1 and DKK-4 play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/βcatenin signaling system. LPR5 and LPR6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/βcatenin signaling cascade. It has been suggested that by inhibiting Wnt/β-catenin signaling, which is essential for posterior patterning in vertebrates, DKK-1 permits anterior development. This notion is supported by the finding that mice deficient of DKK-1 expression lack head formation and die during embryogenesis. Recombinant human DKK-1 expressed in human 293 cells is a 35-40 kDa glycoprotein containing 235 amino-acid residues.

Dkk-1 Polyclonal Antibody

E041928 100μg/100μl
EUR 255
Description: Available in various conjugation types.

Dkk-1 Polyclonal Antibody

E20-75562 100ug
EUR 225
Description: Available in various conjugation types.

Dkk-1 Polyclonal Antibody

ABP53293-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1

Dkk-1 Polyclonal Antibody

ABP53293-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1

Dkk-1 Polyclonal Antibody

ABP53293-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Dkk-1 from Human, Mouse, Rat. This Dkk-1 antibody is for WB, IHC-P, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human Dkk-1

Dkk-1 Recombinant Protein

96-861 0.1 mg
EUR 651.3
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via beta-catenin mediated Pdgfralpha and E-cadherin expression.

Dkk-1 Recombinant Protein

96-990 0.05 mg
EUR 714.3
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via beta-catenin mediated Pdgfralpha and E-cadherin expression.

Dkk-1 Polyclonal Antibody

E44H07004 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

DKK-3 ELISA Kit (Human) (OKBB00603)

OKBB00603 96 Wells
EUR 606
Description: Description of target: Dickkopf-related protein 3 is a protein that in humans is encoded by the DKK3 gene. This gene encodes a protein that is a member of the dickkopf family. It is mapped to 11p15.3. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Members of the Dkk-related family display unique patterns of mRNA expression in human and mouse tissues, and are secreted when expressed in 293T cells. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.;Species reactivity: Human;Application: ELISA;Assay info: Assay Methodology: Quantitative Sandwich Immunoassay;Sensitivity: <= 10 pg/mL

Nori® Human DKK-1 ELISA Kit (2 plates)

GR106268-2 2 x 96-well
EUR 832

Dkk-2

GT15222 100 ug
EUR 631.2

Human DKK-2 Recombinant Protein Lyophilized

IHUDKK2RLY2UG each
EUR 317
Description: Human DKK-2 Recombinant Protein Lyophilized

Human DKK-3 Recombinant Protein Lyophilized

IHUDKK3RLY2UG each
EUR 317
Description: Human DKK-3 Recombinant Protein Lyophilized

Mouse Monoclonal anti-human Dkk-1

hAP-0246 100ug
EUR 250

Mouse Monoclonal anti-human Dkk-1

hAP-0246A 100ug
EUR 250

Sheep Polyclonal anti-Human Dkk-1

hAP-5846 50ug
EUR 400

Biotinylated Recombinant Human Dkk-3 Protein

RP02554 100μg
EUR 1423.5

Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Fc)

PKSH034024-10ug 10ug
EUR 100
Description: Human

Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Fc)

PKSH034024-50ug 50ug
EUR 300
Description: Human

Human Dkk-3 (R335G) Protein, His Tag

DK3-H5220 20ug
EUR 460.1
Description: Human Dkk-3 (R335G), His Tag (DK3-H5220) is expressed from human 293 cells (HEK293). It contains AA Ala 22 - Ile 350 (Accession # Q9UBP4-1 (R335G)).

DKK 1 Recombinant Protein

96-236 0.1 mg
EUR 752.1
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via β-catenin mediated Pdgfrα and E-cadherin expression.

DKK 1 Recombinant Protein

96-237 0.025 mg
EUR 619.8
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK1 takes part in embryonic development through its inhibition of the WNT signaling pathway, binds to LRP6 with high affinity and prevents the Frizzled-Wnt-LRP6 complex formation in response to Wnts. DKK1 promotes LRP6 internalization and degradation when it forms a ternary complex with the cell surface receptor Kremen.DKK1 not olny functions as a head inducer during development, but also regulates joint remodeling and bone formation, which suggests roles for DKK1 in the pathogenesis of rheumatoid arthritis and multiple myeloma. More recently research reported, DKK1 impacts eye development from a defined developmental time point on, and is critical for lens separation from the surface ectoderm via β-catenin mediated Pdgfrα and E-cadherin expression.

Rat DKK-1 ELISA Kit

EK5668 96 tests
EUR 599

Mouse Dkk-1 ELISA Kit

E28L0661 96T
EUR 666.67

Mouse Dkk-1 ELISA KIT

E42EM-173 96T/48T Ask for price

OKRC00364-96W - Dkk-3 ELISA Kit (Human)

OKRC00364-96W 96Wells
EUR 525

OKRC00365-96W - Dkk-4 ELISA Kit (Human)

OKRC00365-96W 96Wells
EUR 525

OKBB00603-96W - DKK-3 ELISA Kit (Human)

OKBB00603-96W 96Wells
EUR 538

DKK-1 (CHO-expressed), Mouse

HY-P7154 50ug
EUR 914.4

Dkk-1 Rabbit Polyclonal Antibody

ES4292-100ul 100ul
EUR 124
Description: A Rabbit Polyclonal antibody against Dkk-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Dkk-1 Rabbit Polyclonal Antibody

ES4292-50ul 50ul
EUR 74
Description: A Rabbit Polyclonal antibody against Dkk-1 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

Recombinant Human DKK-3/DKK3 Protein, His Tag

E40KMH988 20ug
EUR 495

Recombinant Human Dkk-3/DKK3 Protein, His Tag

E40KMP1519 20ug
EUR 495

Dkk-1 Polyclonal Conjugated Antibody

C41928 100ul
EUR 476.4

Dkk-3 antibody

22898 100ul
EUR 479

Dkk-3 antibody

22898-100ul 100ul
EUR 468

Anti-Human Dkk-2 Antibody

102-PA34 200 µg
EUR 204.75
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-11 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-2 has been shown to both inhibit and enhance canonical Wnt signaling; enhancing Wnt signaling through direct high-affinity binding of DKK-2 to LRP6 during LRP6 overexpression, while inhibiting Wnt signaling and promoting LRP6 internalization through the formation of a ternary complex between DKK-2, LRP6, and Kremen-2. Recombinant Human DKK-2 fused to a C terminal His-tag derived from E. coli has a molecular weight of 26.0 kDa and contains 234 amino acid residues.

Anti-Human Dkk-2 Antibody

102-PA34S 100 µg
EUR 126
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-11 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-2 has been shown to both inhibit and enhance canonical Wnt signaling; enhancing Wnt signaling through direct high-affinity binding of DKK-2 to LRP6 during LRP6 overexpression, while inhibiting Wnt signaling and promoting LRP6 internalization through the formation of a ternary complex between DKK-2, LRP6, and Kremen-2. Recombinant Human DKK-2 fused to a C terminal His-tag derived from E. coli has a molecular weight of 26.0 kDa and contains 234 amino acid residues.

Anti-Human Dkk-3 Antibody

101-M470 100 µg
EUR 399
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-l1 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains.  Playing an important regulatory role in vertebrate development through localized inhibition of Wnt regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt /β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-3 has been shown to potentiate, rather than inhibit, Wnt signaling through interactions with the high-affinity, transmembrane coreceptors Kremen-1 (Krm1) and Kremen-2 (Krm2). Recombinant human DKK-3 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 36.3 kDa and contains 329 amino acid residues. Due to glycosylation, human DKK-3 migrates at an apparent molecular weight of approximately 39-49 kDa by SDS-PAGE analysis under non-reducing conditions.

Anti-Human Dkk-4 Antibody

101-M491 100 µg
EUR 399
Description: Dickkopf related protein 4 (Dkk4) is a member of the Dkk protein family that includes Dkk1, 2, 3, and 4. All four members are secreted proteins that are synthesized as precursor proteins with an Nterminal signal peptide and 2 conserved cysteinerich domains, which are separated by a linker region. Dkk proteins have potential furin type proteolytic cleavage sites, and short forms of Dkk2 and Dkk4 containing only the second cysteine-rich domain can be generated by proteolytic processing. Dkk proteins have distinct patterns of expression in adult and embryonic tissues, suggesting that they may play diverse roles in these tissues. The Dkk proteins have distinct effects on Wnt signaling. Dkk1 and Dkk4 are Wnt antagonists. Dkk3 has not been demonstrated to affect Wnt signaling, and Dkk2 acts as an agonist or antagonist, depending on the cellular context.

Mouse Dkk-1 Protein, His Tag

DK1-M52H6 500ug
EUR 374.5
Description: Mouse Dkk-1, His Tag (DK1-M52H6) is expressed from human 293 cells (HEK293). It contains AA Thr 32 - His 272 (Accession # O54908).

Active Recombinant Mouse Dkk-1 Protein

RP01350LQ 100μg
EUR 243.75

Active Recombinant Mouse Dkk-1 Protein

RP01062 5 μg
EUR 390

Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Avi-6His) Biotinylated

PKSH034043-100ug 100ug
EUR 924
Description: Human

Recombinant Human Dickkopf-Related Protein 1/DKK-1 (C-Avi-6His) Biotinylated

PKSH034043-20ug 20ug
EUR 342
Description: Human

Recombinant Human DKK-2/DKK2 Protein, Fc Tag & His Tag.

E40KMH987 20ug
EUR 495

Dkk Polyclonal Antibody

41928 100ul
EUR 319

Human DKK-3(Dickkopf-related protein 3) ELISA Kit

EH0114 96T
EUR 681.12
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 37.5pg/ml

Human DKK-3(Dickkopf-related protein 3) ELISA Kit

EKF60378-48T 48T
EUR 396.9

Human DKK-3(Dickkopf-related protein 3) ELISA Kit

EKF60378-5x96T 5x96T
EUR 2693.25

Human DKK-3(Dickkopf-related protein 3) ELISA Kit

EKF60378-96T 96T
EUR 567

DKK-2 Recombinant Protein

40-651 2 ug
EUR 311.1
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-11 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-2 has been shown to both inhibit and enhance canonical Wnt signaling; enhancing Wnt signaling through direct high-affinity binding of DKK-2 to LRP6 during LRP6 overexpression, while inhibiting Wnt signaling and promoting LRP6 internalization through the formation of a ternary complex between DKK-2, LRP6, and Kremen-2. Recombinant Human DKK-2 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 25.8 kDa and contains 234 amino acid residues. Due to glycosylation, human DKK-2 migrates at an apparent molecular weight of approximately 31-36 kDa by SDS-PAGE analysis under non-reducing conditions.

DKK-3 Recombinant Protein

40-652 2 ug
EUR 311.1
Description: The dickkopf (DKK)-related protein family is comprised of four central members, DKK-1 - 4, along with the distantly-related DKK family member DKK-L1 (Soggy), which is thought to be a descendent of an ancestral DKK-3 precursor due to its unique sequence homology to DKK-3 and no other DKK family member. DKK family members, with the exception of the divergent Soggy, share two conserved cysteine-rich domains and show very little sequence similarity outside of these domains. Playing an important regulatory role in vertebrate development through localized inhibition of Wnt-regulated processes, including anterior-posterior axial patterning, limb development, somitogenesis, and eye formation, DKKs have also been implicated post-developmentally in bone formation, bone disease, cancer, and neurodegenerative diseases. DKK proteins typically play an important regulatory role in the Wnt/β-catenin signaling pathway by forming inhibitory complexes with LDL receptor-related proteins 5 and 6 (LRP5 and LRP6), which are essential components of the Wnt/β-catenin signaling system. LRP5 and LRP6 are single-pass transmembrane proteins that appear to act as co-receptors for Wnt ligands involved in the Wnt/β-catenin signaling cascade. DKK-3 has been shown to potentiate, rather than inhibit, Wnt signaling through interactions with the high-affinity, transmembrane co-receptors Kremen-1 (Krm1) and Kremen-2 (Krm2). Recombinant Human DKK-3 expressed in CHO cells is a glycoprotein that has a calculated molecular weight of 36.3 kDa and contains 329 amino acid residues. Due to glycosylation, Human DKK-3 migrates at an apparent molecular weight of approximately 39-49 kDa by SDS-PAGE analysis under non-reducing conditions.

Dkk-3 Polyclonal Antibody

E20-71355 100ug
EUR 225
Description: Available in various conjugation types.

Dkk-3 Polyclonal Antibody

ABP54542-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160

Dkk-3 Polyclonal Antibody

ABP54542-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160

Dkk-3 Polyclonal Antibody

ABP54542-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of Dkk-3 from Human, Mouse. This Dkk-3 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Dkk-3 at AA rangle: 80-160

Dkk-3 Recombinant Protein

96-991 0.05 mg
EUR 651.3
Description: Members of the dickkopf-related protein family (DKK-1, -2, -3, and -4) are secreted proteins with two cysteine-rich domains separated by a linker region. And DKK3 has been proposed as tumour suppressor gene and a marker for tumour blood vessels. DKK3 is the only DKK family member abundantly expressed in normal lung, but silenced by promoter hypermethylation in a large fraction of lung cancer cell lines and lung tumors. Downregulation of DKK3 was correlated with tumor progression and expression of nuclear beta-catenin in lung tumors. Ectopic expression of DKK3 in lung cancer cells with DKK3 hypermethylation induced apoptosis and inhibited TCF-4 activity as well as nuclear accumulation of beta-catenin and expression of TCF-4 targets c-Myc and cyclin D1. DKK3 modulates FGF and Activin/Nodal signaling to regulate mesoderm induction during early Xenopus development, was reported.

Dkk-3 Polyclonal Antibody

E44H04529 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Nori® Mouse DKK-1 ELISA Kit

GR117408 96-well
EUR 461

Synthetic Biosystem for Modulation of Interactions between Antigen-Presenting Cells and T Cells

T cell activation is triggered by sign molecules on the floor of antigen-presenting cells (APC) and subsequent exertion of mobile forces. Deciphering the biomechanical and biochemical indicators on this advanced course of is of curiosity and can contribute to an enchancment in immunotherapy methods.

To handle underlying questions, coculture and biomimetic fashions are established. Mature dendritic cells (mDC) are first handled with cytochalasin B (CytoB), a cytoskeletal disruption agent identified to decrease obvious mobile stiffness and discount in T cell proliferation is noticed.

It’s tried to imitate mDC and T cell interactions utilizing polyacrylamide (PA) gels with outlined stiffness akin to mDC (0.2-25 kPa). Completely different ratios of anti-CD3 (aCD3) and anti-CD28 (aCD28) antibodies are immobilized onto PA gels.

The outcomes present T cell proliferation is triggered by each aCD3 and aCD28 in a stiffness-dependent method. Cells cultured on aCD3 immobilized on gels has considerably enhanced proliferation and IL-2 secretion, in comparison with aCD28. Moreover, ZAP70 phosphorylation is enhanced in stiffer substrate a in a aCD3-dependent method.

The biosystem supplies an strategy to review the discount of T cell proliferation noticed on CytoB-treated mDC. Total, the biosystem permits distinguishing the affect of biophysical and biochemical indicators of APC and T cell interactions in vitro.

Graphene-based nanomaterials in biosystems.

Graphene-based nanomaterials have emerged as a novel sort of supplies with distinctive physicochemical properties and quite a few functions in varied areas. On this overview, we summarize latest advances in finding out interactions between graphene and biosystems.

We first present a short introduction on graphene and its derivatives, after which focus on on the toxicology and biocompatibility of graphene, together with the extracellular interactions between graphene and biomacromolecules, mobile research of graphene, and in vivo toxicological results.

Subsequent, we concentrate on varied graphene-based sensible functions in antibacterial supplies, wound addressing, drug supply, and water purification. We lastly current views on challenges and future developments in these thrilling fields.

Preface: Management and Design of Biosystems.

Biosystems are dynamic networks pushed by cross-scale interactions between molecules, cells, tissues, organs and organisms. Latest advances in our understanding of the spatiotemporal regulation and group of biosystems have stimulated exploration of novel approaches to regulate and design biosystems at a number of organic scales.

Such new approaches embrace synthetic cell synthesis, technology of embryoids/organoids, reconstitution and manipulation of life occasions corresponding to getting old and replica, and multidisciplinary approaches utilizing theoretical and engineering applied sciences. These control-and-design methodologies are anticipated to open up a new avenue to understanding life occasions in addition to to supply the idea for novel design methods in medical sciences.

KIR2DL4

CSB-CL857457HU 10 μg plasmid + 200μl Glycerol Ask for price

KIR2DL4

pro-2460 1µg
EUR 60
Description: Recombinant Human Killer Cell Immunoglobulin-Like Receptor, 2 Domains Long Cytoplasmic Tail 4

NE Purified anti-human CD158d (KIR2DL4)

E16FHY158d-050U 50 μg
EUR 845
Description: Available in various conjugation types.

KIR2DL4 Antibody

DF13591 100ul
EUR 420

KIR2DL4 Antibody

DF13591-100ul 100ul
EUR 280

KIR2DL4 Antibody

DF13591-200ul 200ul
EUR 350

KIR2DL4 Antibody

E912836 100ul
EUR 255
Description: Available in various conjugation types.

KIR2DL4 Antibody

E309374 200ul
EUR 275
Description: Available in various conjugation types.

KIR2DL4 antibody

70R-2365 50 ug
EUR 467
Description: Rabbit polyclonal KIR2DL4 antibody raised against the middle region of KIR2DL4

KIR2DL4 Antibody

GWB-MP022D 50ug Ask for price

Human KIR2DL4 Protein, Fc Tag

E40KMPH4155 20ug
EUR 495

Human KIR2DL4 Protein, Fc Tag

E40KMPH4156 20ug
EUR 495

KIR2DL4 Recombinant Protein (Human)

RP017041 100 ug Ask for price

KIR2DL4 ORF Vector (Human) (pORF)

ORF005681 1.0 ug DNA
EUR 114

Human KIR2DL4 knockout cell line

ABC-KH7929 1 vial Ask for price
Description: Human KIR2DL4 knockout cell line is HEK293/HeLa cell line, edited by CRISPR/Cas9 technology.

Human KIR2DL4 knockdown cell line

ABC-KD7929 1 vial Ask for price
Description: Human KIR2DL4 knockdown cell line is engineered by our optimized transduction of the specific shRNA with lentivirus. Knockdown levels are determined via qRT-PCR. Gentaur offers generation of stable knockdown (RNAi) cell lines expressing shRNAs targeting genes of your interest.

Human KIR2DL4 Protein Lysate 20ug

IHUKIR2DL4PLLY20UG each
EUR 213
Description: Human KIR2DL4 Protein Lysate 20ug

KIR2DL3 / KIR2DL1 / KIR2DL4 / KIR2DS4 Antibody

20-abx210854
  • Ask for price
  • Ask for price
  • 100 ul
  • 50 ul

KIR2DL3 / KIR2DL1 / KIR2DL4 / KIR2DS4 Antibody

20-abx339417
  • Ask for price
  • Ask for price
  • 100 ul
  • 50 ul

KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4 Antibody

1-CSB-PA205578
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4. Recognizes KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:2000-1:5000, IHC:1:50-1:200

KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4 Antibody

1-CSB-PA246816
  • Ask for price
  • Ask for price
  • 100ul
  • 50ul
Description: A polyclonal antibody against KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4. Recognizes KIR2DL3/KIR2DL1/KIR2DL4/KIR2DS4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:1000-1:2000, IHC:1:50-1:100

KIR2DL3 / KIR2DL1 / KIR2DL4 / KIR2DS4 Antibody

abx210854-100l 100 µl
EUR 350

KIR2DL3 / KIR2DL1 / KIR2DL4 / KIR2DS4 Antibody

abx210854-50l 50 µl
EUR 250

KIR2DL3 / KIR2DL1 / KIR2DL4 / KIR2DS4 Antibody

abx339417-100l 100 µl
EUR 350

KIR2DL3 / KIR2DL1 / KIR2DL4 / KIR2DS4 Antibody

abx339417-50l 50 µl
EUR 250

KIR2DL4 siRNA

20-abx921662
  • Ask for price
  • Ask for price
  • 15 nmol
  • 30 nmol

Recombinant Human KIR2DL4/CD158D Protein

PKSH030752-100ug 100ug
EUR 732
Description: Human

Human KIR2DL4 / CD158d Protein, Fc Tag

KI4-H5255 100ug
EUR 2749.9
Description: Human KIR2DL4, Fc Tag (KI4-H5255) is expressed from human 293 cells (HEK293). It contains AA His 24 - His 242 (Accession # Q99706-1).

KIR2DL4 Polyclonal Antibody

27806 100ul
EUR 439

KIR2DL4 Polyclonal Antibody

27806-100ul 100ul
EUR 302.4

KIR2DL4 Polyclonal Antibody

27806-50ul 50ul
EUR 224.4

KIR2DL4 Polyclonal Antibody

E-AB-64343-120uL 120uL
EUR 320
Description: Unconjugated

KIR2DL4 Polyclonal Antibody

E-AB-64343-200uL 200uL
EUR 530
Description: Unconjugated

KIR2DL4 Polyclonal Antibody

E-AB-64343-60uL 60uL
EUR 200
Description: Unconjugated

KIR2DL4 Polyclonal Antibody

E-AB-64343-each each Ask for price
Description: Unconjugated

Recombinant Human KIR2DL4 Protein, His Tag

E40KMH1307 20ug
EUR 495

Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His)

AP75042 1mg
EUR 3209

Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His)

C310-10ug 10ug
EUR 157.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His)

C310-1mg 1mg
EUR 2739.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His)

C310-500ug 500ug
EUR 1935.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Recombinant Human KIR2DL4/CD158d/KIR103 (C-6His)

C310-50ug 50ug
EUR 327.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

KIR2DL4 sgRNA CRISPR Lentivector set (Human)

K1150301 3 x 1.0 ug
EUR 406.8

KIR2DL4 Rabbit pAb

A12836-100ul 100 ul
EUR 369.6

KIR2DL4 Rabbit pAb

A12836-200ul 200 ul
EUR 550.8

KIR2DL4 Rabbit pAb

A12836-20ul 20 ul
EUR 219.6

KIR2DL4 Rabbit pAb

A12836-50ul 50 ul
EUR 267.6

KIR2DL4 Rabbit pAb

E2511314 100ul
EUR 225
Description: Available in various conjugation types.

KIR2DL4 Rabbit mAb

A23918 200μL
EUR 1557.4
Description: Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human p70 S6 Kinase 2 (Q9UBS0).

KIR2DL4 Protein Vector (Human) (pPM-C-HA)

PV022723 500 ng
EUR 394.8

KIR2DL4 Protein Vector (Human) (pPB-C-His)

PV022721 500 ng
EUR 394.8

KIR2DL4 Protein Vector (Human) (pPB-N-His)

PV022722 500 ng
EUR 394.8

KIR2DL4 Protein Vector (Human) (pPM-C-His)

PV022724 500 ng
EUR 394.8

KIR2DL4 cloning plasmid

CSB-CL857457HU-10ug 10ug
EUR 279.6
Description: A cloning plasmid for the KIR2DL4 gene.

KIR2DL4 Blocking Peptide

33R-9831 100 ug
EUR 119
Description: A synthetic peptide for use as a blocking control in assays to test for specificity of KIR2DL4 antibody, catalog no. 70R-2365

Recombinant Human KIR2DL4/CD158D Protein (His Tag)

PKSH032675-10ug 10ug
EUR 98
Description: Human

Recombinant Human KIR2DL4/CD158D Protein (His Tag)

PKSH032675-50ug 50ug
EUR 262
Description: Human

OAEE00659-100T - KIR2DL4 Antibody

OAEE00659-100T 100tests
EUR 299

OAEE00660-100T - KIR2DL4 Antibody

OAEE00660-100T 100tests
EUR 299

Recombinant Human KIR2DL4 Protein, His, Insect-1ug

QP12489-1ug 1ug
EUR 186

Recombinant Human KIR2DL4 Protein, His, Insect-5ug

QP12489-5ug 5ug
EUR 241.2

OAEE00101-100UG - KIR2DL4 Antibody

OAEE00101-100UG 0.1mg
EUR 259

OAGA02475-100UL - KIR2DL4 Antibody

OAGA02475-100UL 100ul
EUR 369

KIR2DL4 Rabbit Polyclonal Antibody

E10G30445 100 μl
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

KIR2DL4 Recombinant Protein

91-290 0.05 mg
EUR 556.8
Description: Killer cell immunoglobulin-like receptor 2DL4(KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.

Recombinant Human KIR2DL4 Protein, His, Insect-50ug

QP12489-50ug 50ug
EUR 1513.2

Recombinant Human CD158D/KIR2DL4 Protein, His Tag

E40KMH335 20ug
EUR 495

KIR2DL4 sgRNA CRISPR Lentivector (Human) (Target 1)

K1150302 1.0 ug DNA
EUR 184.8

KIR2DL4 sgRNA CRISPR Lentivector (Human) (Target 2)

K1150303 1.0 ug DNA
EUR 184.8

KIR2DL4 sgRNA CRISPR Lentivector (Human) (Target 3)

K1150304 1.0 ug DNA
EUR 184.8

KIR2DL4 Polyclonal Conjugated Antibody

C27806 100ul
EUR 476.4

KIR2DL4 (untagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 1

SC126103 10 µg Ask for price

KIR2DL4 (untagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 2

SC319875 10 µg Ask for price

KIR2DL4 (untagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 3

SC315741 10 µg Ask for price

Human KIR2DL4 Recombinant Protein C-6 His Tag Lyophilized

IHUKIR2DL4RC6HISLY50UG each
EUR 640
Description: Human KIR2DL4 Recombinant Protein C-6 His Tag Lyophilized

KIR2DL4 (GFP-tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 3

RG214254 10 µg Ask for price

KIR2DL4 (GFP-tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 1

RG214354 10 µg Ask for price

KIR2DL4 (GFP-tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 2

RG208307 10 µg Ask for price

KIR2DL4 (Human) - 3 unique 27mer siRNA duplexes - 2 nmol each

SR320789 2 nmol Ask for price

Lenti ORF particles, KIR2DL4 (Myc-DDK tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4),

RC214354L3V 200 µl Ask for price

Lenti ORF particles, KIR2DL4 (Myc-DDK tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4),

RC214254L3V 200 µl Ask for price

KIR2DL4 (Myc-DDK-tagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 2

RC208307 10 µg Ask for price

Lenti ORF particles, KIR2DL4 (mGFP-tagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), trans

RC208307L4V 200 µl Ask for price

KIR2DL4 (Myc-DDK-tagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 1

RC214354 10 µg Ask for price

Lenti ORF particles, KIR2DL4 (mGFP-tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), tra

RC214354L4V 200 µl Ask for price

KIR2DL4 (Myc-DDK-tagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcript variant 3

RC214254 10 µg Ask for price

Lenti ORF particles, KIR2DL4 (mGFP-tagged) - Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), tra

RC214254L4V 200 µl Ask for price

ARP42025_P050-25UL - KIR2DL4 Antibody - middle region

ARP42025_P050-25UL 25ul
EUR 99

OCOA15270-20UG - KIR2DL4 Protein Lysate

OCOA15270-20UG 20ug
EUR 169

OCOA14196-20UG - KIR2DL4 Protein Lysate

OCOA14196-20UG 20ug
EUR 169

KIR2DL4 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)

K1150305 3 x 1.0 ug
EUR 451.2

KIR2DL4 Over-expression Lysate Product

GWB-F8A916 0.1 mg Ask for price

Lenti ORF particles, KIR2DL4 (Myc-DDK-tagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), tr

RC208307L3V 200 µl Ask for price

Lenti-ORF clone of KIR2DL4 (mGFP-tagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), transcr

RC208307L4 10 µg Ask for price

Human Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Protein

abx693714-10nmol 10 nmol Ask for price

Human Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Protein

abx693714-5nmol 5 nmol
EUR 837.5

Human Killer cell immunoglobulin-like receptor 2DL4 (KIR2DL4) Protein

abx680209-10g 10 µg
EUR 225

Human Killer cell immunoglobulin-like receptor 2DL4 (KIR2DL4) Protein

abx680209-50g 50 µg
EUR 325

Human Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Protein

abx690660-100ml 100 ml
EUR 362.5

Human Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Protein

abx690660-50ml 50 ml
EUR 200

ARP42025_P050 - KIR2DL4 antibody - middle region (ARP42025_P050)

ARP42025_P050 100ul
EUR 389

Lenti-ORF clone of KIR2DL4 (Myc-DDK-tagged)-Human killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4), tran

RC208307L3 10 µg Ask for price

Human KIR2DL4 / Killer cell immunoglobulin-like receptor 2DL4 ELISA Kit

E15363h 96T
EUR 736

KIR2DL4 3'UTR GFP Stable Cell Line

TU061796 1.0 ml
EUR 1825.2

KIR2DL4 mouse monoclonal antibody, clone mAb#33, PE

AM26033RP-N 100 Tests Ask for price

KIR2DL4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 1)

K1150306 1.0 ug DNA
EUR 200.4

KIR2DL4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)

K1150307 1.0 ug DNA
EUR 200.4

KIR2DL4 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 3)

K1150308 1.0 ug DNA
EUR 200.4

Human Killer cell immunoglobulin-like receptor 2DL4 (KIR2DL4) ELISA Kit

SL3301Hu 96 Tests
EUR 468

Human Killer cell immunoglobulin-like receptor 2DL4 (KIR2DL4) ELISA Kit

abx529938-96tests 96 tests
EUR 687.5

KIR2DL4 mouse monoclonal antibody, clone mAb#33, APC

AM26033AC-N 100 Tests Ask for price

ARP76327_P050-25UL - KIR2DL4 Antibody - C-terminal region

ARP76327_P050-25UL 25ul
EUR 99

OAAB05630-400UL - KIR2DL4 Antibody - C-terminal region

OAAB05630-400UL 400ul
EUR 409

KIR2DL4 - Human, 4 unique 29mer shRNA constructs in lentiviral GFP vector

TL311899 5 µg/vial Ask for price

AAP42025-100UG - KIR2DL4 Peptide - middle region

AAP42025-100UG 100ug
EUR 99

KIR2DL4 3'UTR Luciferase Stable Cell Line

TU011796 1.0 ml
EUR 1825.2

ARP76327_P050 - KIR2DL4 Antibody - C-terminal region (ARP76327_P050)

ARP76327_P050 100ul
EUR 389

KIR2DL4 (C-term) rabbit polyclonal antibody, Aff - Purified

AP52370PU-N 400 µl Ask for price

KIR2DL4 - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector

TR311899 5 µg/vial Ask for price

KIR2DL4 mouse monoclonal antibody, clone mAb#33, Aff - Purified

AM26033PU-N 100 µg Ask for price

Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Antibody

abx145740-100ug 100 ug
EUR 469.2

Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Antibody

abx145740-1096tests 10 × 96 tests Ask for price

Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Antibody

abx145740-596tests 5 × 96 tests Ask for price

Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Antibody

abx145740-96tests 96 tests
EUR 337.5

Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Antibody

abx140618-100g 100 µg
EUR 350

KIR2DL4 (L1, L3, L4, S4) mouse monoclonal antibody, clone 2H6, Purified

SM6021 100 µl Ask for price

KIR2DL4 (L1, L3, L4, S4) mouse monoclonal antibody, clone 2H6, Purified

SM6021S 50 µl Ask for price

Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Antibody (APC / Cyanine 7)

abx140994-100g 100 µg
EUR 437.5

Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Antibody (PE / Cyanine 5)

abx347049-100l 100 µl Ask for price

Killer Cell Immunoglobulin-Like Receptor 2DL4 (KIR2DL4) Antibody (PE / Cyanine 5)

abx347049-50l 50 µl
EUR 400

Rabbit Anti KIR2DL4 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot)

IRBAMLKIR2DL4AP343120UL each
EUR 346
Description: Rabbit Anti KIR2DL4 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot)

Rabbit Anti KIR2DL4 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot)

IRBAMLKIR2DL4AP343200UL each
EUR 509
Description: Rabbit Anti KIR2DL4 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Western Blot)

KIR2DL4 Killer Cell Immunoglobulin-Like Receptor, 2 Domains Long Cytoplasmic Tail 4 Human Recombinant Protein

PROTQ99706 Regular: 5ug
EUR 380.4
Description: KIR2DL4 Human Recombinant produced in Sf9 Insect cells is a single, glycosylated polypeptide chain containing 458 amino acids (24-242 a.a.) and having a molecular mass of 51kDa (Molecular size on SDS-PAGE will appear at approximately 50-70kDa). KIR2DL4 is expressed with a 239 amino acids hIgG-His tag at C-Terminus and purified by proprietary chromatographic techniques. 

Anti-Human KIR2DL1 Antibody

101-M539 100 µg
EUR 399
Description: The KIR gene family currently consists of 15 gene loci (KIR2DL1, KIR2DL2/L3, KIR2DL4, KIR2DL5A, KIR2DL5B, KIR2DS1, KIR2DS2, KIR2DS3, KIR2DS4, KIR2DS5, KIR3DL1/S1, KIR3DL2, KIR3DL3 and two pseudogenes, KIR2DP1 and KIR3DP1) encoded within a 100-200 Kb region of the Leukocyte Receptor Complex (LRC) located on chromosome 19 (19q13.4). The LRC constitutes a large, 1 Mb, and dense cluster of rapidly evolving immune genes which contains genes encoding other cell surface molecules with distinctive Ig-like extra-cellular domains. These genes include, from centromere to telomere, Leukocyte Immunoglobulin-like Receptors (LILR) and Leukocyte-Associated Immunoglobulin-like Receptors (LAIR), FcGammaR as well as the Natural cytotoxicity-triggering Receptor 1 (NCR1). In addition the extended LRC contains genes encoding the Sialic acid binding Immunoglobulin-like Lectins (SIGLEC) and the CD66 family members such as the carcino-embryonic antigen (CEA) genes as well as the genes encoding the transmembrane adaptor molecules DAP10 and DAP12.

Anti-Human KIR2DL3 Antibody

101-M540 100 µg
EUR 399
Description: The KIR gene family currently consists of 15 gene loci (KIR2DL1, KIR2DL2/L3, KIR2DL4, KIR2DL5A, KIR2DL5B, KIR2DS1, KIR2DS2, KIR2DS3, KIR2DS4, KIR2DS5, KIR3DL1/S1, KIR3DL2, KIR3DL3 and two pseudogenes, KIR2DP1 and KIR3DP1) encoded within a 100-200 Kb region of the Leukocyte Receptor Complex (LRC) located on chromosome 19 (19q13.4). The LRC constitutes a large, 1 Mb, and dense cluster of rapidly evolving immune genes which contains genes encoding other cell surface molecules with distinctive Ig-like extra-cellular domains. These genes include, from centromere to telomere, Leukocyte Immunoglobulin-like Receptors (LILR) and Leukocyte-Associated Immunoglobulin-like Receptors (LAIR), FcGammaR as well as the Natural cytotoxicity-triggering Receptor 1 (NCR1). In addition the extended LRC contains genes encoding the Sialic acid binding Immunoglobulin-like Lectins (SIGLEC) and the CD66 family members such as the carcino-embryonic antigen (CEA) genes as well as the genes encoding the transmembrane adaptor molecules DAP10 and DAP12.

Anti-Human KIR3DL1 Antibody

101-M543 100 µg
EUR 399
Description: The KIR gene family currently consists of 15 gene loci (KIR2DL1, KIR2DL2/L3, KIR2DL4, KIR2DL5A, KIR2DL5B, KIR2DS1, KIR2DS2, KIR2DS3, KIR2DS4, KIR2DS5, KIR3DL1/S1, KIR3DL2, KIR3DL3 and two pseudogenes, KIR2DP1 and KIR3DP1) encoded within a 100-200 Kb region of the Leukocyte Receptor Complex (LRC) located on chromosome 19 (19q13.4). The LRC constitutes a large, 1 Mb, and dense cluster of rapidly evolving immune genes which contains genes encoding other cell surface molecules with distinctive Ig-like extra-cellular domains. These genes include, from centromere to telomere, Leukocyte Immunoglobulin-like Receptors (LILR) and Leukocyte-Associated Immunoglobulin-like Receptors (LAIR), FcGammaR as well as the Natural cytotoxicity-triggering Receptor 1 (NCR1). In addition the extended LRC contains genes encoding the Sialic acid binding Immunoglobulin-like Lectins (SIGLEC) and the CD66 family members such as the carcino-embryonic antigen (CEA) genes as well as the genes encoding the transmembrane adaptor molecules DAP10 and DAP12.

PE anti-human CD158f (KIR2DL5)

E16FHP158f-025 25 tests
EUR 541.67
Description: Available in various conjugation types.

PE anti-human CD158f (KIR2DL5)

E16FHP158f-100 100 tests
EUR 1256.67
Description: Available in various conjugation types.

Human KIR2DL3 Antibody

32965-05111 150 ug
EUR 215

PE anti-human CD158e1 (KIR3DL1, NKB1)

E16FHP158e-025 25 tests
EUR 433.33
Description: Available in various conjugation types.

PE anti-human CD158e1 (KIR3DL1, NKB1)

E16FHP158e-100 100 tests
EUR 953.33
Description: Available in various conjugation types.

Mouse Monoclonal anti-human KIR2DL1

hAP-0439 100ug
EUR 250

Mouse Monoclonal anti-human KIR2DL3

hAP-0440 100ug
EUR 250

Mouse Monoclonal anti-human KIR3DL1

hAP-0443 100ug
EUR 250

APC anti-human CD158e1 (KIR3DL1, NKB1)

E16FHA158e-025 25 tests
EUR 411.67
Description: Available in various conjugation types.

APC anti-human CD158e1 (KIR3DL1, NKB1)

E16FHA158e-100 100 tests
EUR 1105
Description: Available in various conjugation types.

PE anti-human CD158 (KIR2DL1/S1/S3/S5)

E16FHP158-025 25 tests
EUR 520
Description: Available in various conjugation types.

PE anti-human CD158 (KIR2DL1/S1/S3/S5)

E16FHP158-100 100 tests
EUR 1083.33
Description: Available in various conjugation types.

PE anti-human CD158 (KIR2DL1/S1/S3/S5)

E16FHP158a-025 25 tests
EUR 520
Description: Available in various conjugation types.

PE anti-human CD158 (KIR2DL1/S1/S3/S5)

E16FHP158a-100 100 tests
EUR 1083.33
Description: Available in various conjugation types.

KIR2DL4 - Human shRNA lentiviral particles (4 unique 29mer target-specific shRNA, 1 scramble control), 0.5 ml each, >10^7 TU/ml.

TL311899V 500 ul each Ask for price

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